RCT Abstract - Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomized, double-blind, placebo-controlled, phase 3 trial

被引：2

作者：

Naccache, Jean-Marc ^{[1
]}

Jouneau, Stephane ^{[2
]}

Didier, Morgane ^{[3
]}

Borie, Raphael ^{[4
]}

Cachanado, Marine ^{[5
]}

Bourdin, Arnaud ^{[6
]}

Reynaud-Gaubert, Martine ^{[7
]}

Bonniaud, Philippe ^{[8
]}

Israel-Biet, Dominique ^{[9
]}

Prevot, Gregoire ^{[10
]}

Hirschi, Sandrine ^{[11
]}

Lebargy, Francois ^{[12
]}

Marchand-Adam, Sylvain ^{[13
]}

Bautin, Nathalie ^{[14
]}

Traclet, Julie ^{[15
]}

Gomez, Emmanuel ^{[16
]}

Leroy, Sylvie ^{[17
]}

Gagnadoux, Frederic ^{[18
]}

Riviere, Frederic ^{[19
]}

Bergot, Emmanuel ^{[20
]}

Gondouin, Anne ^{[21
]}

Blanchard, Elodie ^{[22
]}

Parrot, Antoine ^{[23
]}

Blanc, Francois-Xavier ^{[24
]}

Chabrol, Alexandre ^{[25
]}

Dominique, Stephane ^{[26
]}

Gibelin, Aude ^{[27
]}

Tazi, Abdellatif ^{[28
]}

Berard, Laurence ^{[5
]}

Brillet, Pierre-Yves ^{[29
]}

Debray, Marie-Pierre ^{[30
]}

Rousseau, Alexandra ^{[5
]}

Kerjouan, Malorie ^{[2
]}

Freynet, Olivia ^{[31
]}

Dombret, Marie-Christine ^{[4
]}

Gamez, Anne-Sophie ^{[6
]}

Nieves, Ana ^{[7
]}

Beltramo, Guillaume ^{[8
]}

Pastre, Jean ^{[9
]}

Le Borgne-Krams, Aurelie ^{[10
]}

Degot, Tristan

Launois, Claire ^{[12
]}

Plantier, Laurent ^{[13
]}

Wemeau-Stervinou, Lidwine

Cadranel, Jacques

Chenivesse, Cecile ^{[14
]}

Valeyre, Dominique ^{[3
]}

Crestani, Bruno ^{[4
]}

Cottin, Vincent

Simon, Tabassome ^{[5
]}

机构：

[1] Grp Hosp Paris St Joseph, Serv Pneumol, Paris, France

[2] Hop Pontchaillou, Serv Pneumol, Rennes, France

[3] Hop Avicenne, AP HP, Ctr Constitutif Malad Pulmonaires Rares Adulte, Serv Pneumol & Oncol Thorac, Bobigny, France

[4] Hop Bichat Claude Bernard, AP HP, Serv Pneumol A,FHU APOLLO, Ctr Reference Constitutif Malad Pulm Rares, Paris, France

[5] Hop St Antoine, AP HP, Dept Clin Pharmacol & Clin Res Platform East Pari, Paris, France

[6] Univ Montpellier, CHU Montpellier, Dept Resp Dis, Montpellier, France

[7] Hop Nord Marseille, AP HM, CHU Marseille, Pneumol, Marseille, France

[8] Ctr Hosp Univ Dijon Bourgogne, Serv Pneumol & Soins Intensifs Resp, Ctr Reference Constitutif Malad Pulm Rares, Serv Pneumol, Dijon, France

[9] CHU Hop Europeen Georges Pompidou, AP HP, Serv Pneumol, Paris, France

[10] Hop Larrey, Serv Pneumol, Toulouse, France

[11] Hop Univ Strasbourg, Serv Pneumol, Nouvel Hop Civil, Strasbourg, France

[12] CHU Maison Blanche, Serv Malad Resp, Reims, France

[13] CHRU Tours, Serv Pneumol & Dexplorat Fonct Resp, Tours, France

[14] Hop Calmette, Ctr Reference Constitutif Malad Pulm Rares, CHU Lille, Serv Pneumol & Immuno Allergol, Lille, France

[15] Hop Louis Pradel, Hosp Civils Lyon, Ctr Cordonnateur Natl Reference Malad Pulmo, Lyon, France

[16] Poles Specialites Medic CHRU Brabois, Dept Pneumol, Nancy, Vandoeuvre Nanc, France

[17] Univ Cote Azur, CHU Nice, Dept Pneumol, Nice, France

[18] Univ Angers, Dept Pneumol, CHU Angers, Angers, France

[19] Hop Instruct Armees Percy, Serv Pneumol, Clamart, France

[20] CHU Cote Nacre, Serv Pneumol & Oncol Thorac, Caen, France

[21] CHU Jean Minjoz, Serv Pneumol, Besancon, France

[22] Hop Haut Leveque, CHU Bordeaux, Serv Malad Resp, Bordeaux, France

[23] Hop Tenon, AP HP, Ctr Constitutif Malad Pulm Rares Iadulte &, Serv Pneumol & Oncol Thorac, Paris, France

[24] Nantes Univ Hosp, Dept Resp Med, Inst Thorax, Nantes, France

[25] Hop Foch, Serv Pneumol, Suresnes, France

[26] Rouen Univ Hosp, Dept Pneumol, CIC CRB 1404, Rouen, France

[27] Hop Tenon, AP HP, Serv Reanimat, Paris, France

[28] Hop St Louis, AP HP, Serv Pneumol, Ctr Natl Reference Histiocytoses, Paris, France

[29] Serv Radiol, APHP, Hop Avicenne, Bobigny, France

[30] Hop Bichat Claude Bernard, AP HP, Serv Radiol, Paris, France

[31] Hop Avicenne, AP HP, Serv Pneumol & Oncol Thorac, Ctr Constitutif Malad Pulm Rares Ladulte, Bobgny, France

来源：

EUROPEAN RESPIRATORY JOURNAL | 2021年 / 58卷

关键词：

Idiopathic pulmonary fibrosis; Treatments; Exacerbation;

D O I：

10.1183/13993003.congress-2021.RCT2903

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

RCT2903

引用

页数：4