Preparation of 2-, 4-, 5-, and 6-aminonicotinic acid tert-butyl esters

被引：3
|
作者：
Wright, Stephen W. [1 ]
机构：
[1] Pfizer Global Res & Dev, Groton, CT 06340 USA
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 49卷 / 02期
关键词：
INHIBITORS; DERIVATIVES; ANALOGS;
D O I：
10.1002/jhet.799
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Procedures are reported to prepare the tert-butyl esters of 2-aminonicotinic acid, 4-aminonicotinic acid, 5-aminonicotinic acid, and 6-aminonicotinic acid from 2-chloronicotinic acid, 4-chloronicotinic acid, 5-bromonicotinic acid, and 6-chloronicotinic acid, respectively, without need for purification of intermediates. J. Heterocyclic Chem., (2012).
引用
收藏
页码：442 / 445
页数：4
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