Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions

被引：18

作者：

Chaudhuri, Subrata Kumar ^{[2
]}

Roy, Sanchita ^{[3
]}

Bhar, Sanjay ^{[1
]}

机构：

[1] Jadavpur Univ, Dept Chem, Organ Chem Sect, Kolkata 700032, India

[2] Khorop High Sch, Howrah, W Bengal, India

[3] Basanti Devi Coll, Dept Chem, Kolkata 700029, India

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 8卷

关键词：

coumarins; solvent-free reaction; substituents; vinylic bromination; SELECTIVE BROMINATION;

D O I：

10.3762/bjoc.8.35

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituents on the outcome of the reaction have been rationalized with a proposed mechanism.

引用

页码：323 / 329

页数：7

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