The potential use of cell-based therapies in the treatment of oral diseases

被引：9

作者：

Kagami, H. ^{[1
,2
,3
]}

机构：

[1] Matsumoto Dent Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Shiojiri, Nagano 3990781, Japan

[2] Univ Tokyo, Inst Med Sci, Tissue Engn Res Grp, Div Mol Therapy,Adv Clin Res Ctr, Tokyo, Japan

[3] Univ Tokyo, Inst Med Sci, IMSUT Hosp, Clin Bone Regenerat,Dept Adv Med Sci, Tokyo, Japan

来源：

ORAL DISEASES | 2015年 / 21卷 / 05期

关键词：

cell therapy; tissue engineering; regenerative medicine; bone regeneration; salivary gland regeneration; SALIVARY-GLAND FUNCTION; WHOLE-BODY IRRADIATION; TISSUE-ENGINEERED BONE; MESENCHYMAL STEM-CELLS; HUMAN DENTAL-PULP; MARROW TRANSPLANTATION; IN-VITRO; REGENERATION; EXPANSION; CARTILAGE;

D O I：

10.1111/odi.12320

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

A recent and exciting development in medicine is the use of living cells for patient treatment. The utility of living cells to treat diseases was first proved in hematopoietic stem cell transplantation for leukemia patients. This approach has been expanded for other diseases such as islet transplantation for diabetic patients. In those cases, the cells were isolated from donors or the patient and used without complex manipulation. Since the 1980s, cells have been expanded outside of the body for the treatment of burn patients' skin. This novel treatment strategy is designated tissue engineering' and has been successfully applied for treatment of skin, cartilage, and also bone defects. Due to the recent developments in stem cell science, this area has attracted much attention and the application has been expanding. In this review, the potential of cell-based therapy for oral diseases is discussed with a concise review of recent developments in this field.

引用

页码：545 / 549

页数：5

共 44 条

[1] Effective bone engineering with periosteum-derived cells [J].