Lack of evidence for systemic cytomegalovirus reactivation in maintenance hemodialysis patients

被引：3

作者：

Pliquett, R. U. ^{[1
]}

Klein, C. ^{[2
]}

Gruenewald, T. ^{[3
]}

Ruf, B. R. ^{[3
]}

Beige, J. ^{[1
,3
]}

机构：

[1] Kuratorium Dialyse & Nierentransplantat Nierenzen, Renal Unit, D-04129 Leipzig, Germany

[2] Hosp St Georg, Dept Lab Med & Mol Diagnost, Leipzig, Germany

[3] Hosp St Georg, Dept Infect Dis & Nephrol, Leipzig, Germany

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2011年 / 30卷 / 12期

关键词：

TRANSPLANT RECIPIENTS; T-CELLS; INFECTION; ACTIVATION; NAIVE; RISK;

D O I：

10.1007/s10096-011-1260-8

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The risk of cytomegalovirus (CMV) reactivation among hemodialysis (HD) patients is unknown. In 52 HD patients from a single center, CMV serology and quantitative PCR were performed. The detection limit of PCR was 20 copies/ml. Here, PCR ruled out CMV viremia, despite CMV-IgM seropositivity in 15.4% patients.

引用

页码：1557 / 1560

页数：4

共 15 条

[1] CMV Seropositivity Determines Epoetin Dose and Hemoglobin Levels in Patients with CKD [J].

Betjes, Michiel G. H. ;

Weimar, Willem ;

Litjens, Nicolle H. R. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 20 (12) :2661-2666

[2] The impact of cytomegalovirus infection ≥1 year after primary renal transplantation [J].

Browne, Barry J. ;

Young, Jo-Anne ;

Dunn, Ty B. ;

Matas, Arthur J. .

CLINICAL TRANSPLANTATION, 2010, 24 (04) :572-577

[3] AIDS-defining opportunistic illnesses in US patients, 1994-2007: a cohort study [J].

Buchacz, Kate ;

Baker, Rose K. ;

Palella, Frank J., Jr. ;

Chmiel, Joan S. ;

Lichtenstein, Kenneth A. ;

Novak, Richard M. ;

Wood, Kathleen C. ;

Brooks, John T. .

AIDS, 2010, 24 (10) :1549-1559

[4] T-CELL ACTIVATION DEFECT IN HEMODIALYSIS-PATIENTS - EVIDENCE FOR A ROLE OF THE B7/CD28 PATHWAY [J].

GIRNDT, M ;

KOHLER, H ;

SCHIEDHELMWEICK, E ;

ZUMBUSCHENFELDE, KHM ;

FLEISCHER, B .

KIDNEY INTERNATIONAL, 1993, 44 (02) :359-365

[5] Monitoring of cytomegalovirus infection in solid-organ transplant recipients by an ultrasensitive plasma PCR assay [J].

Hadaya, K ;

Wunderli, W ;

Deffernez, C ;

Martin, PY ;

Mentha, G ;

Binet, I ;

Perrin, L ;

Kaiser, L .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (08) :3757-3764

[6] Evasion of CD8+ T Cells Is Critical for Superinfection by Cytomegalovirus [J].

Hansen, Scott G. ;

Powers, Colin J. ;

Richards, Rebecca ;

Ventura, Abigail B. ;

Ford, Julia C. ;

Siess, Don ;

Axthelm, Michael K. ;

Nelson, Jay A. ;

Jarvis, Michael A. ;

Picker, Louis J. ;

Frueh, Klaus .

SCIENCE, 2010, 328 (5974) :102-106

[7] Improved monitoring of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation by an ultrasensitive plasma DNA PCR assay [J].

Kaiser, L ;

Perrin, L ;

Chapuis, B ;

Hadaya, K ;

Kolarova, L ;

Deffernez, C ;

Huguet, S ;

Helg, C ;

Wunderli, W .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (11) :4251-4255

[8] Cytomegalovirus Infection Renal Transplant Recipients: Risk Factors and Outcome [J].

Kanter, J. ;

Pallardo, L. ;

Gavela, E. ;

Escudero, V. ;

Beltran, S. ;

Morales, A. ;

Avila, A. ;

Crespo, J. F. .

TRANSPLANTATION PROCEEDINGS, 2009, 41 (06) :2156-2158

[9] EFFECT OF PRIMARY EPSTEIN-BARR VIRUS-INFECTION ON HUMAN HERPESVIRUS-6, CYTOMEGALOVIRUS, AND MEASLES-VIRUS IMMUNOGLOBULIN-G TITERS [J].

LINDE, A ;

FRIDELL, E ;

DAHL, H ;

ANDERSSON, J ;

BIBERFELD, P ;

WAHREN, B .

JOURNAL OF CLINICAL MICROBIOLOGY, 1990, 28 (02) :211-215

[10] Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes [J].

Litjens, NHR ;

van Druningen, CJ ;

Betjes, MGH .

CLINICAL IMMUNOLOGY, 2006, 118 (01) :83-91

← 1 2 →