I2/KI-Mediated Oxidative N-N Bond Formation for the Synthesis of 1,5-Fused 1,2,4-Triazoles from N-Aryl Amidines

被引：69

作者：

Song, Lina ^{[1
]}

Tian, Xianhai ^{[1
]}

Lv, Zhigang ^{[1
]}

Li, Ertong ^{[1
]}

Wu, Jie ^{[1
]}

Liu, Yangxue ^{[1
]}

Yu, Wenquan ^{[1
]}

Chang, Junbiao ^{[1
,2
]}

机构：

[1] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China

[2] Collaborat Innovat Ctr New Drug Res & Safety Eval, Zhengzhou 450001, Henan Province, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 80卷 / 14期

基金：

中国博士后科学基金; 中国国家自然科学基金;

关键词：

MOLECULAR-IODINE; ORGANIC-SYNTHESIS; METAL-FREE; SELECTIVE INHIBITOR; DERIVATIVES; DISCOVERY; EFFICIENT; TRIAZOLOPYRIDINES; ALDEHYDES; SYSTEM;

D O I：

10.1021/acs.joc.5b01183

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An I-2/KI-mediated oxidative N-N bond formation reaction is described. This new and environmentally benign approach allows for the convenient synthesis of a variety of 1,2,4-triazolo [1,5-a]pyridines and other 1,5-fused 1,2,4-triazoles from readily available N-aryl amidines in an efficient and scalable fashion.

引用

页码：7219 / 7225

页数：7

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