Association between coffee consumption and an oxidative stress marker in women

Coffee is one of the major dietary modulators of oxidative stress conditions. Whether coffee consumption is associated with oxidative stress markers, such as derivatives of reactive oxygen metabolites (d-ROMs), remains to be investigated in women, despite one recent report describing their significant association in men. A total of 415 women (49 +/- 9 years) attending a general clinic were evaluated regarding their self-reported coffee consumption habits and blood d-ROMs levels. Women who reported a parts per thousand yenaEuro parts per thousand 3 cups/day of coffee consumption displayed a lower d-ROMs level than those who reported consuming 0-2 cups/day (336 +/- 67 vs. 358 +/- 80 Carr U; p < 0.05). In the multivariate-adjusted analysis, the association between coffee consumption and the d-ROMs level remained to be significant (p < 0.05). Daily coffee consumption (i.e., a parts per thousand yenaEuro parts per thousand 3 cups) may be associated with a reduced oxidative stress status, as measured by the d-ROMs level, among women.