Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence

被引:30
作者
Barbara, Giussy [1 ,2 ,3 ]
Buggio, Laura [4 ]
Facchin, Federica [5 ]
Vercellini, Paolo [3 ,4 ]
机构
[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Obstet & Gynaecol Emergency Dept, Milan, Italy
[2] Fdn IRCCS Ca Granda Osped Maggiore Policlin, SVSeD Serv Sexual & Domest Violence, Milan, Italy
[3] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy
[4] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Gynaecol Unit, Milan, Italy
[5] Univ Cattolica Sacro Cuore, Dept Psychol, Milan, Italy
来源
FRONTIERS IN GLOBAL WOMENS HEALTH | 2021年 / 2卷
关键词
endometriosis; medical treatment; estrogen-progestins; GnRH agonists; GnRH antagonists; quality of life; tolerability; NORETHINDRONE ACETATE; PELVIC PAIN; HORMONE-ANTAGONIST; CONSEQUENCES; IMPACT; WOMEN; LINZAGOLIX; MANAGEMENT; ELAGOLIX;
D O I
10.3389/fgwh.2021.729601
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Endometriosis is associated with painful symptoms, infertility, sexological difficulties, and psychological suffering. All these symptoms have a negative impact on the overall quality of life of women with the disease, with significant personal, social and economic costs. Several medical options are available to manage symptomatic endometriosis. The pharmacological treatment for endometriosis-related pain may be necessary for decades, or at least until there is a desire for pregnancy or physiologic menopause occurs. In this perspective, clinicians should consider not only the efficacy, but also side effects, tolerability, and costs, along with women's preferences toward different treatments. In this mini-review, we analyzed the pros and cons of the available drugs for the medical therapy of endometriosis, such as estrogen-progestins, progestins, GnRH agonist and GnRH antagonists.
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页数:6
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