Positive Multifocal PSMA PET/CT in a Patient With Prostate Cancer and Follicular Lymphoma

被引:4
作者
Dendl, Katharina [1 ]
Merkel, Andreas [1 ]
Kratochwil, Clemens [1 ]
Choyke, Peter L. [2 ]
Kleist, Christian [1 ]
Cardinale, Jens [1 ,3 ]
Haberkorn, Uwe [1 ,4 ,5 ]
Giesel, Frederik L. [1 ,3 ,6 ]
机构
[1] Univ Hosp Heidelberg, Dept Nucl Med, INF 400, D-69120 Heidelberg, Germany
[2] NCI, Mol Imaging Program, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
[3] Univ Hosp Dusseldorf, Dept Nucl Med, Dusseldorf, Germany
[4] German Canc Res Ctr, Clin Cooperat Unit Nucl Med, Heidelberg, Germany
[5] German Ctr Lung Res, Translat Lung Res Ctr Heidelberg, Heidelberg, Germany
[6] Natl Ctr Tumor Dis, Heidelberg, Germany
关键词
PSMA PET/CT; prostate cancer; follicular lymphoma;
D O I
10.1097/RLU.0000000000003828
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
ABSTRACT: Prostate-specific membrane antigen (PSMA) PET/CT is a highly reliable nuclear tracer for diagnostic imaging of prostate cancer. However, PSMA is also expressed by some nonprostatic tissues such as benign tumors, inflammatory processes, and malignant neoplasms. This case presents a patient with prostate cancer and follicular lymphoma undergoing PSMA PET/CT. Remarkably, both tumor entities were clearly detected in the scan. Yet, the 2 malignancies demonstrated rather different ranges in terms of SUVmax uptake values and therefore still enabled precise and accurate discrimination of prostate cancer and follicular lymphoma. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码:E47 / E48
页数:2
相关论文
共 8 条
[1]   The role of PSMA PET/CT imaging in the diagnosis, staging and restaging of prostate cancer [J].
Bagguley, Dominic ;
Ong, Sean ;
Buteau, James P. ;
Koschel, Sam ;
Dhiantravan, Nattakorn ;
Hofman, Michael S. ;
Emmett, Louise ;
Murphy, Declan G. ;
Lawrentschuk, Nathan .
FUTURE ONCOLOGY, 2021, 17 (17) :2225-2241
[2]   F-18 labelled PSMA-1007: biodistribution, radiation dosimetry and histopathological validation of tumor lesions in prostate cancer patients [J].
Giesel, Frederik L. ;
Hadaschik, B. ;
Cardinale, J. ;
Radtke, J. ;
Vinsensia, M. ;
Lehnert, W. ;
Kesch, C. ;
Tolstov, Y. ;
Singer, S. ;
Grabe, N. ;
Duensing, S. ;
Schaefer, M. ;
Neels, O. C. ;
Mier, W. ;
Haberkorn, U. ;
Kopka, K. ;
Kratochwil, C. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 (04) :678-688
[3]   Head-to-Head Comparison of 68Ga-PSMA-11 with 18F-PSMA-1007 PET/CT in Staging Prostate Cancer Using Histopathology and Immunohistochemical Analysis as a Reference Standard [J].
Kuten, Jonathan ;
Fahoum, Ibrahim ;
Savin, Ziv ;
Shamni, Ofer ;
Gitstein, Gilad ;
Hershkovitz, Dov ;
Mabjeesh, Nicola J. ;
Yossepowitch, Ofer ;
Mishani, Eyal ;
Even-Sapir, Einat .
JOURNAL OF NUCLEAR MEDICINE, 2020, 61 (04) :527-532
[4]  
Malaspina S, 2021, EUR J NUCL MED MOL I, V48, P2951, DOI 10.1007/s00259-021-05296-1
[5]   Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer-Updated Diagnostic Utility, Sensitivity, Specificity, and Distribution of Prostate-specific Membrane Antigen-avid Lesions: A Systematic Review and Meta-analysis [J].
Perera, Marlon ;
Papa, Nathan ;
Roberts, Matthew ;
Williams, Michael ;
Udovicich, Cristian ;
Vela, Ian ;
Christidis, Daniel ;
Bolton, Damien ;
Hofman, Michael S. ;
Lawrentschuk, Nathan ;
Murphy, Declan G. .
EUROPEAN UROLOGY, 2020, 77 (04) :403-417
[6]   Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging [J].
Sheikhbahaei, Sara ;
Afshar-Oromieh, Ali ;
Eiber, Matthias ;
Solnes, Lilja B. ;
Javadi, Mehrbod S. ;
Ross, Ashley E. ;
Pienta, Kenneth J. ;
Allaf, Mohamad E. ;
Haberkorn, Uwe ;
Pomper, Martin G. ;
Gorin, Michael A. ;
Rowe, Steven P. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 44 (12) :2117-2136
[7]  
Silver DA, 1997, CLIN CANCER RES, V3, P81
[8]   Radiolabeled prostate-specific membrane antigen small-molecule inhibitors [J].
Wil, Leon ;
Soni, Ida ;
Kopka, Klaus ;
Kratochwil, Clemens ;
Giesel, Frederik L. ;
Haberkorn, Uwe .
QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2017, 61 (02) :168-180