Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in Leon, Nicaragua

被引:3
作者
Gonzalez, Fredman [1 ]
Vielot, Nadja A. [2 ]
Sciaudone, Michael [3 ]
Toval-Ruiz, Christian [1 ]
Premkumar, Lakshmanane [4 ]
Gutierrez, Lester [1 ]
Cuadra, Edwing Centeno [1 ]
Munguia, Nancy [1 ]
Blandon, Patricia [1 ]
de Silva, Aravinda M. [4 ]
Rubinstein, Rebecca [5 ]
Bowman, Natalie [3 ]
Becker-Dreps, Sylvia [2 ]
Bucardo, Filemon [1 ]
机构
[1] Natl Autonomous Univ Nicaragua Leon, Ctr Infect Dis Res, Leon, Nicaragua
[2] Univ N Carolina, Dept Family Med, Chapel Hill, NC 27515 USA
[3] Univ N Carolina, Div Infect Dis, Chapel Hill, NC 27515 USA
[4] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27515 USA
[5] Univ N Carolina, Sch Med, Chapel Hill, NC 27515 USA
关键词
COVID-19; epidemiology; Nicaragua; SARS-CoV-2; seroprevalence;
D O I
10.1017/S0950268821002144
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.
引用
收藏
页数:6
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