Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in Leon, Nicaragua

被引：3

作者：

Gonzalez, Fredman ^{[1
]}

Vielot, Nadja A. ^{[2
]}

Sciaudone, Michael ^{[3
]}

Toval-Ruiz, Christian ^{[1
]}

Premkumar, Lakshmanane ^{[4
]}

Gutierrez, Lester ^{[1
]}

Cuadra, Edwing Centeno ^{[1
]}

Munguia, Nancy ^{[1
]}

Blandon, Patricia ^{[1
]}

de Silva, Aravinda M. ^{[4
]}

Rubinstein, Rebecca ^{[5
]}

Bowman, Natalie ^{[3
]}

Becker-Dreps, Sylvia ^{[2
]}

Bucardo, Filemon ^{[1
]}

机构：

[1] Natl Autonomous Univ Nicaragua Leon, Ctr Infect Dis Res, Leon, Nicaragua

[2] Univ N Carolina, Dept Family Med, Chapel Hill, NC 27515 USA

[3] Univ N Carolina, Div Infect Dis, Chapel Hill, NC 27515 USA

[4] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27515 USA

[5] Univ N Carolina, Sch Med, Chapel Hill, NC 27515 USA

来源：

EPIDEMIOLOGY & INFECTION | 2021年 / 149卷

关键词：

COVID-19; epidemiology; Nicaragua; SARS-CoV-2; seroprevalence;

D O I：

10.1017/S0950268821002144

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.

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