CD8 T-Cell Lymphocytosis and Associated Clinical Syndromes in HIV-Infected Patients

被引：0
作者：
Tiberio, Perry J. [1 ]
Ogbuagu, Onyema E. [2 ]
机构：
[1] Yale New Haven Med Ctr, 20 York St, New Haven, CT 06504 USA
[2] Yale Univ, Sch Med, Infect Dis Sect, Yale AIDS Program, New Haven, CT USA
来源：
AIDS REVIEWS | 2015年 / 17卷 / 04期
关键词：
HIV infection; HIV-1; Human; Lymphocytosis; IMMUNODEFICIENCY VIRUS-1 INFECTION; CD4CD8; RATIO; HIV-1-INFECTED PATIENTS; SICCA SYNDROME; CD4(+); ACTIVATION; RESPONSES; DISEASE; ENCEPHALITIS; ANTIGEN;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
An inverted CD4:CD8 T lymphocyte ratio is frequently observed in individuals infected with HIV. A subset of these individuals develops an exuberant and persistent CD8 T-cell lymphocytosis response to HIV infection that may occur despite virologic suppression on treatment and has been associated with adverse clinical effects and disorders. This review describes clinical syndromes that have been reported primarily in HIV-infected individuals with CD8 T-cell lymphocytosis including their presentation, management, and clinical outcomes where known.
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页码：202 / 211
页数：10
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