Central nervous system Aspergillus infection after epidural analgesia: diagnosis, therapeutic challenges, and literature review

被引:18
作者
Genzen, Jonathan R. [1 ]
Kenney, Barton [1 ,2 ]
机构
[1] Yale Univ, Sch Med, Dept Lab Med, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06520 USA
基金
美国国家卫生研究院;
关键词
Central nervous system; Aspergillus; Epidural anesthesia; INVASIVE ASPERGILLOSIS; CEREBRAL ASPERGILLOSIS; CEREBROSPINAL-FLUID; FUNGAL-INFECTIONS; SRI-LANKA; MENINGITIS; PATIENT; HYDROCEPHALUS; GALACTOMANNAN; VORICONAZOLE;
D O I
10.1016/j.diagmicrobio.2009.06.013
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Aspergillus terreus was identified in an intradural spinal biopsy specimen from an African female with recurrent headache and hydrocephalus. Prior laboratory testing of cerebrospinal fluid was nondiagnostic, despite extensive central nervous system (CNS) involvement. CNS Aspergillus infection presents a diagnostic and therapeutic challenge and is reviewed in the context of this particularly instructive and difficult case. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:312 / 318
页数:7
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