Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins.

被引:5
作者
Candiani, I [1 ]
Bedeschi, A [1 ]
Cabri, W [1 ]
Zarini, F [1 ]
Visentin, G [1 ]
Capolongo, L [1 ]
Geroni, C [1 ]
Ciomei, M [1 ]
机构
[1] PHARMACIA & UPJOHN INC,I-20014 NERVIANO,MI,ITALY
关键词
D O I
10.1016/S0960-894X(97)00105-4
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new family of camptothecin derivatives is described. Their synthesis, in vitro cytotoxicity, and topoisomerase I inhibition is reported. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:847 / 850
页数:4
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