Synthesis and bioactivity of a-aminophosphonates containing fluorine

被引：52

作者：

Song, BA ^{[1
]}

Wu, YL ^{[1
]}

Yang, S ^{[1
]}

Hu, DY ^{[1
]}

He, XQ ^{[1
]}

Jin, LH ^{[1
]}

机构：

[1] Guizhou Univ, Res & Dev Ctr Fine Chem, Guiyang 550025, Peoples R China

来源：

MOLECULES | 2003年 / 8卷 / 01期

关键词：

a-aminophosphonates; synthesis; bioactivity;

D O I：

10.3390/80100186

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Twenty-one a-aminophosphonates containing fluorine were synthesized by Mannich-type reactions. Their structures were established by elemental analysis, IR, H-1-NMR and MS. In field tests, some of these new compounds display high antiviral activity against the tobacco mosaic virus (TMV). The molecular geometry of compound 4f was determined by X-ray difliraction structure analysis.

引用

页码：186 / 192

页数：7

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