DETECTION OF SYNCHRONOUS LUNG TUMORS IN PATIENTS PRESENTING WITH SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK

被引：16
作者：
Ghosh, Samit K. [1 ,2 ]
Roland, Nicholas J. [1 ]
Kumar, Aman [1 ]
Tandon, Sankalap [1 ,2 ]
Lancaster, Jeffrey L. [1 ]
Jackson, Shaun R. [1 ]
Jones, Andrew [2 ]
Jones, Huw Lewis [3 ]
Hanlon, Rebecca [3 ]
Jones, Terry M. [1 ,2 ]
机构：
[1] Aintree Univ Hosp NHS Fdn Trust, Dept Otolaryngol Head & Neck Surg, Liverpool L9 7AL, Merseyside, England
[2] Univ Liverpool, Sch Canc Studies, Liverpool L69 3GA, Merseyside, England
[3] Aintree Univ Hosp NHS Fdn Trust, Dept Radiol, Liverpool L9 7AL, Merseyside, England
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2009年 / 31卷 / 12期
关键词：
head and neck neoplasms; squamous cell carcinoma; lung neoplasm; metastasis; mass screening; CHEST COMPUTED-TOMOGRAPHY; NEWLY-DIAGNOSED HEAD; DISTANT METASTASES; CANCER; ABDOMEN;
D O I：
10.1002/hed.21124
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Background. Screening for synchronous pulmonary tumors in patients presenting with squamous cell carcinoma of the head and neck (SCCHN) is important, because detection may alter subsequent management. Methods. We conducted a retrospective review, comparing effectiveness of pulmonary screening using thoracic CT or chest X-ray, in 1882 patients presenting with SCCHN. Results. The overall rate of synchronous pulmonary tumors was 4.3%. The number needed to scan, ie, the number of thoracic CTs required to detect 1 pulmonary tumor, is reported for recurrent primary tumors, primary disease load (T and N classification), and individual primary sites. The incidence of pulmonary metastases is related to locoregional disease load while the incidence of bronchogenic carcinoma is sporadic. Conclusion. Although it is possible to propose a pragmatic screening protocol for pulmonary metastases, this is not possible for bronchogenic carcinomas. Therefore, we recommend that thoracic CT is used in all cases to screen for coexistent pulmonary pathology. (C) 2009 Wiley Periodicals, Inc. Head Neck 31: 1563-1570, 2009
引用
收藏
页码：1563 / 1570
页数：8
相关论文
共 13 条
[1]  
[Anonymous], EFF HEAD NECK CANC M
[2]   Lung cancer screening: Recommendation statement [J].
Berg, AO ;
Allan, JD ;
Frame, P ;
Homer, CJ ;
Klein, JD ;
Lieu, TA ;
Orleans, CT ;
Peipert, JF ;
Siu, AL ;
Teutsch, SM ;
Westhoff, C ;
Woolf, SH .
ANNALS OF INTERNAL MEDICINE, 2004, 140 (09) :738-739
[3]   Screening for distant metastases in patients with head and neck cancer: Is chest computed tomography sufficient? [J].
Brouwer, J ;
de Bree, R ;
Hoekstra, OS ;
Golding, RP ;
Langendijk, JA ;
Castelijns, JA ;
Leemans, CR .
LARYNGOSCOPE, 2005, 115 (10) :1813-1817
[4]   Screening for distant metastases in patients with head and neck cancer [J].
de Bree, R ;
Deurloo, EE ;
Snow, GB ;
Leemans, CR .
LARYNGOSCOPE, 2000, 110 (03) :397-401
[5]  
Jäckel MC, 1999, HNO, V47, P38, DOI 10.1007/s001060050356
[6]   Efficacy of radiologic screening for distant metastases and second primaries in newly diagnosed patients with head and neck cancer [J].
Jaeckel, Martin C. .
LARYNGOSCOPE, 2007, 117 (02) :242-247
[7]   CT of the chest and abdomen in patients with newly diagnosed head and neck squamous cell carcinoma [J].
Keski-Säntti, HT ;
Markkola, ATO ;
Mäkitie, AA ;
Bäck, LJJ ;
Atula, TS .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2005, 27 (10) :909-915
[8]   A rational approach to pulmonary screening in newly diagnosed head and neck cancer [J].
Loh, KS ;
Brown, DH ;
Baker, JT ;
Gilbert, RW ;
Gullane, PJ ;
Irish, JC .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2005, 27 (11) :990-994
[9]   Radiological staging of the chest and abdomen in head and neck squamous cell carcinoma - are computed tomography and ultrasound necessary? [J].
Nilssen, ELK ;
Murthy, P ;
McClymont, L ;
Denholm, S .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1999, 113 (02) :152-154
[10]  
Office for National Statistics, 2010, CANC STAT REG REG CA
12