How to diagnose parkinsonian central pain?

被引：25

作者：

Marques, Ana ^{[1
]}

Attal, Nadine ^{[2
,3
]}

Bouhassira, Didier ^{[2
,3
]}

Moisset, Xavier ^{[4
,5
]}

Cantagrel, Nathalie ^{[6
]}

Rascol, Olivier ^{[7
]}

Durif, Franck ^{[1
]}

Brefel-Courbon, Christine ^{[7
]}

机构：

[1] Univ Clermont Auvergne, Neurol Dept, Clermont Ferrand Univ Hosp, EA7280,NS Pk FCRIN Network, Clermont Ferrand, France

[2] Univ Paris Saclay, INSERM U 987, F-92100 Boulogne, France

[3] Univ Paris Saclay, CHU Arnbroise Pare, APHP, CETD, F-92100 Boulogne, France

[4] Univ Clermont Auvergne, Inserm U1107, NeuroDol, Clermont Ferrand, France

[5] CHU Clermont Ferrand, Clermont Ferrand, France

[6] Toulouse Univ Hosp, Pain Dept, Toulouse, France

[7] Univ Toulouse 3, Dept Clin Pharmacol & Neurosci, Ctr Invest Clin CIC1436,INSERM, NS Pk FCRIN Network,UMR ToNIC 1214,Univ Hosp Toul, Toulouse, France

来源：

PARKINSONISM & RELATED DISORDERS | 2019年 / 64卷

关键词：

Parkinson; Central pain; Diagnosis; Classification; Criteria; DISEASE; STIMULATION; PERCEPTION; THRESHOLD; LEVODOPA;

D O I：

10.1016/j.parkreldis.2019.04.025

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Among the different types of pain observed in Parkinson's disease, parkinsonian central pain (PCP) has the highest severity, and is poorly characterized and difficult to describe not only by patients but also by neurologists. Thus PCP remains not strictly defined and is difficult to distinguish from other types of pain on the basis of clinical description. Yet, standardizing PCP diagnosis is critical to improve the treatment of this debilitating pain subtype, but also to homogenize further studies investigating the pathophysiological mechanisms underlying this condition. Accounting for the lack of reliable validated positive clinical criteria for PCP, and as the clinical features of PCP are difficult to specify, we suggest to consider so far the gold standard diagnosis of PCP mainly based on exclusion criteria. We propose a new algorithm aiming to disentangle PCP from other chronic pain subtypes in Parkinson's disease, by sequentially ruling out what PCP is not.

引用

页码：50 / 53

页数：4

共 28 条

[1] Assessment and manifestation of central sensitisation across different chronic pain conditions [J].