Effective therapy for murine model of adult T-cell leukemia with anti-CD2 monoclonal antibody, MEDI-507.

被引:0
|
作者
Zhuo, Z [1 ]
Zhang, ML [1 ]
Mandler, R [1 ]
Goldman, C [1 ]
Morris, JC [1 ]
Janick, JE [1 ]
Waldmann, TA [1 ]
机构
[1] NCI, NIH, Metab Branch, Bethesda, MD 20892 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
3021
引用
收藏
页码:763A / 763A
页数:1
相关论文
共 50 条
  • [1] Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD2 monoclonal antibody, MEDI-507
    Zhang, Z
    Zhang, ML
    Ravetch, JV
    Goldman, C
    Waldmann, TA
    BLOOD, 2003, 102 (01) : 284 - 288
  • [2] Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD52 monoclonal antibody, Campath-1H
    Zhang, Z
    Zhang, ML
    Goldman, CK
    Ravetch, JV
    Waldmann, TA
    CANCER RESEARCH, 2003, 63 (19) : 6453 - 6457
  • [3] Population Pharmacokinetics of Siplizumab (MEDI-507), a Humanized Anti-CD2 Monoclonal Antibody, in Cancer Patients.
    Chen, Chunlin
    Janik, John E.
    Kaucic, Karen
    Roskos, Lorin
    Jallal, Bahija
    Robbie, Gabriel J.
    BLOOD, 2009, 114 (22) : 1046 - 1046
  • [4] MONOCLONAL ANTI-CD44 ANTIBODY ACTS IN SYNERGY WITH ANTI-CD2 BUT INHIBITS ANTI-CD3 OR T-CELL RECEPTOR-MEDIATED SIGNALING IN MURINE T-CELL HYBRIDOMAS
    GUO, YJ
    MA, J
    WONG, JH
    LIN, SC
    CHANG, HC
    BIGBY, M
    SY, MS
    CELLULAR IMMUNOLOGY, 1993, 152 (01) : 186 - 199
  • [5] Anti-CD2 monoclonal antibody and tacrolimus in adult liver transplantation
    Lerut, J
    Van Thuyne, V
    Mathijs, J
    Lemaire, J
    Talpe, W
    Roggen, F
    Ciccarelli, O
    Zuckermann, M
    Goffette, P
    Hope, J
    Gianello, P
    Bazin, H
    Cornet, A
    Rahier, J
    Latinne, D
    TRANSPLANTATION, 2005, 80 (09) : 1186 - 1193
  • [6] Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies
    Spitzer, TR
    McAfee, SL
    Dey, BR
    Colby, C
    Hope, J
    Grossberg, H
    Preffer, F
    Shaffer, J
    Alexander, SI
    Sachs, DH
    Sykes, M
    TRANSPLANTATION, 2003, 75 (10) : 1748 - 1751
  • [7] EBV-Related Lymphoproliferative Disease Complicating Therapy with the Anti-CD2 Monoclonal Antibody, Siplizumab, in Patients with T-Cell Malignancies
    O'Mahony, Deirdre
    Morris, John C.
    Stetler-Stevenson, Maryalice
    Matthews, Helen
    Brown, Margaret R.
    Fleisher, Thomas
    Pittaluga, Stefania
    Raffeld, Mark
    Albert, Paul S.
    Reitsma, Dirk
    Kaucic, Karen
    Hammershaimb, Luz
    Waldmann, Thomas A.
    Janik, John E.
    CLINICAL CANCER RESEARCH, 2009, 15 (07) : 2514 - 2522
  • [8] Combination therapy for adult T-cell leukemia-xenografted mice: flavopiridol and anti-CD25 monoclonal antibody
    Zhang, ML
    Zhang, Z
    Goldman, CK
    Janik, J
    Waldmann, TA
    BLOOD, 2005, 105 (03) : 1231 - 1236
  • [9] Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine
    Shaffer, Juanita
    Villard, Jean
    Means, Terry K.
    Alexander, Stephen
    Dombkowski, David
    Dey, Bimalangshu R.
    McAfee, Steven
    Ballen, Karen K.
    Saidman, Susan
    Preffer, Frederic I.
    Sachs, David H.
    Spitzer, Thomas R.
    Sykes, Megan
    EXPERIMENTAL HEMATOLOGY, 2007, 35 (07) : 1140 - 1152
  • [10] MONOCLONAL ANTI-TAC ANTIBODY - A POTENTIAL CARRIER FOR IMMUNOTOXIN THERAPY IN ADULT T-CELL LEUKEMIA
    KRONKE, M
    DEPPER, JM
    LEONARD, WJ
    VITETTA, ES
    WALDMANN, TA
    GREENE, WC
    CLINICAL RESEARCH, 1984, 32 (02): : A418 - A418