Dexmedetomidine: perioperative applications in children

被引:56
作者
Yuen, Vivian Man Ying [1 ,2 ]
机构
[1] Queen Mary Hosp, Dept Anaesthesiol, Pokfulam, Hong Kong, Peoples R China
[2] Univ Hong Kong, Dept Anaesthesiol, Hong Kong, Hong Kong, Peoples R China
关键词
dexmedetomidine; pediatric anesthesia; perioperative applications; INCREASING PLASMA-CONCENTRATIONS; ORAL CLONIDINE PREMEDICATION; RANDOMIZED CONTROLLED-TRIAL; DOSE DEXMEDETOMIDINE; INTRANASAL DEXMEDETOMIDINE; INTRAOCULAR-PRESSURE; INTRAVENOUS DEXMEDETOMIDINE; ANESTHETIC REQUIREMENTS; SEVOFLURANE ANESTHESIA; SEDATIVE PREMEDICATION;
D O I
10.1111/j.1460-9592.2009.03207.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
P>Dexmedetomidine is a highly specific and selective alpha-2-adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be explored. In this review, various uses of dexmedetomidine are discussed in detail.
引用
收藏
页码:256 / 264
页数:9
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