Transgenic mouse models of tumour angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models

被引:190
作者
Hanahan, D
Christofori, G
Naik, P
Arbeit, J
机构
[1] RES INST MOL PATHOL, A-1030 VIENNA, AUSTRIA
[2] UNIV CALIF SAN FRANCISCO, DEPT SURG, SAN FRANCISCO, CA 94143 USA
关键词
D O I
10.1016/S0959-8049(96)00401-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:2386 / 2393
页数:8
相关论文
共 44 条
[31]   BOVINE PAPILLOMAVIRUS GENOME ELICITS SKIN TUMORS IN TRANSGENIC MICE [J].
LACEY, M ;
ALPERT, S ;
HANAHAN, D .
NATURE, 1986, 322 (6080) :609-612
[32]   Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4 [J].
Lee, J ;
Gray, A ;
Yuan, J ;
Luoh, SM ;
Avraham, H ;
Wood, WI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (05) :1988-1992
[33]  
NAIK PN, 1996, GENE DEV, V13, P1847
[34]   Vascular endothelial growth factor B, a novel growth factor for endothelial cells [J].
Olofsson, B ;
Pajusola, K ;
Kaipainen, A ;
vonEuler, G ;
Joukov, V ;
Saksela, O ;
Orpana, A ;
Petersson, RF ;
Alitalo, K ;
Eriksson, U .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (06) :2576-2581
[35]  
PARANGI S, 1995, CANCER RES, V55, P6071
[36]   Antiangiogenic therapy of transgenic mice impairs de novo tumor growth [J].
Parangi, S ;
OReilly, M ;
Christofori, G ;
Holmgren, L ;
Grosfeld, J ;
Folkman, J ;
Hanahan, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (05) :2002-2007
[37]  
RAK J, 1995, CANCER RES, V55, P4575
[38]   CONSEQUENCES OF ANGIOGENESIS FOR TUMOR PROGRESSION, METASTASIS AND CANCER-THERAPY [J].
RAK, JW ;
STCROIX, BD ;
KERBEL, RS .
ANTI-CANCER DRUGS, 1995, 6 (01) :3-18
[39]  
ROBERTS WG, 1995, J CELL SCI, V108, P2369
[40]   VASCULAR ENDOTHELIAL GROWTH-FACTOR INDUCED BY HYPOXIA MAY MEDIATE HYPOXIA-INITIATED ANGIOGENESIS [J].
SHWEIKI, D ;
ITIN, A ;
SOFFER, D ;
KESHET, E .
NATURE, 1992, 359 (6398) :843-845