Enzymatic biofuel cells utilizing a biomimetic cofactor

被引：75

作者：

Campbell, Elliot ^{[1
]}

Meredith, Matthew ^{[2
]}

Minteer, Shelley D. ^{[2
]}

Banta, Scott ^{[1
]}

机构：

[1] Columbia Univ City New York, Dept Chem Engn, New York, NY 10027 USA

[2] Dept Chem & Mat Sci & Engn, Salt Lake City, UT 84112 USA

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 13期

关键词：

2,5-DIKETO-D-GLUCONIC ACID REDUCTASE; DEHYDROGENASE ENZYMES; STEADY-STATE; SPECIFICITY; ELECTRODES; SUBSTRATE; OXIDATION; NAD(+); NAFION; LIVER;

D O I：

10.1039/c2cc16156g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The performance of immobilized enzyme systems is often limited by cofactor diffusion and regeneration. Here, we demonstrate an engineered enzyme capable of utilizing the minimal cofactor nicotinamide mononucleotide (NMN+) to address these limitations. Significant gains in performance are observed with NMN+ in immobilized systems, despite a decreased turnover rate with the minimal cofactor.

引用

页码：1898 / 1900

页数：3

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