Antiradical and antioxidant activity of total anthocyanins from Perilla pankinensis decne

被引：159
作者：
Gülçin, I
Berashvili, D
Gepdiremen, A
机构：
[1] Ataturk Univ, Fac Sci & Arts, Dept Chem, TR-25240 Erzurum, Turkey
[2] Tbilisi State Med Univ, Fac Pharm, Dept Pharmacognosy, Tbilisi, Georgia
[3] Ondokuz Mayis Univ, Fac Med, Dept Pharmacol, TR-55050 Samsun, Turkey
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 2005年 / 101卷 / 1-3期
关键词：
anthocyanin; antioxidant activity; metal chelating; radical scavenging; Perilla pankinensis; Labiatae;
D O I：
10.1016/j.jep.2005.05.006
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The purpose of this work comprise the assessment of the antioxidant activity of total anthocyanins from Perilla pankinensis samples (TAPP) by different analytical methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH center dot) free radical scavenging, total antioxidant activity, total reducing activity, superoxide anion radical scavenging, hydrogen peroxide scavenging and metal chelating activities. Total antioxidant activity was measured according to ferric thiocyanate method. a-Tocopherol and trolox, which water-soluble analogue of tocopherol were used as references antioxidant compounds. At the concentrations of 30 and 45 mu g/mL, TAPP showed 91.9 and 96.4% inhibition on lipid peroxidation of linoleic acid emulsion, respectively. In comparison, 45 mu g/mL of standard antioxidant such as alpha-tocopherol and trolox exhibited 88.8 and 86.2% inhibition on peroxidation of linoleic acid emulsion, respectively. In addition, TAPP have found effective on DPPH center dot scavenging, superoxide anion radical and hydrogen peroxide scavenging, total reducing power and metal chelating on ferrous ions activities. Also, these various antioxidant effects were compared to alpha-tocopherol and trolox. (C) 2005 Elsevier Ireland Ltd. All rights reserved.
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收藏
页码：287 / 293
页数：7
相关论文
共 51 条
[1]   ANTIOXIDANT DETERMINATIONS BY THE USE OF A STABLE FREE RADICAL [J].
BLOIS, MS .
NATURE, 1958, 181 (4617) :1199-1200
[2]   LEUKOCYTE-MEDIATED INACTIVATION OF ALPHA-1-PROTEINASE INHIBITOR IS INHIBITED BY AMINO ANALOGS OF ALPHA-TOCOPHEROL [J].
BOLKENIUS, FN .
BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1095 (01) :23-29
[3]   In vitro antioxidant properties of dantrolene sodium [J].
Büyükokuroglu, ME ;
Gülçin, I ;
Oktay, M ;
Küfrevioglu, Ö .
PHARMACOLOGICAL RESEARCH, 2001, 44 (06) :491-494
[4]   Antioxidative activity and safety of the 50% ethanolic extract from red bean fermented by Bacillus subtilis IMR-NK1 [J].
Chung, YC ;
Chang, CT ;
Chao, WW ;
Lin, CF ;
Chou, ST .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2002, 50 (08) :2454-2458
[5]   Antioxidant properties of hydroxy-flavones [J].
Cotelle, N ;
Bernier, JL ;
Catteau, JP ;
Pommery, J ;
Wallet, JC ;
Gaydou, EM .
FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (01) :35-43
[6]   DNA oxidative damage during differentiation of HL-60 human promyelocytic leukemia cells [J].
Covacci, V ;
Torsello, A ;
Palozza, P ;
Sgambato, A ;
Romano, G ;
Boninsegna, A ;
Cittadini, A ;
Wolf, FI .
CHEMICAL RESEARCH IN TOXICOLOGY, 2001, 14 (11) :1492-1497
[7]   ACTION OF PHENOLIC DERIVATIVES (ACETAMINOPHEN, SALICYLATE, AND 5-AMINOSALICYLATE) AS INHIBITORS OF MEMBRANE LIPID-PEROXIDATION AND AS PEROXYL RADICAL SCAVENGERS [J].
DINIS, TCP ;
MADEIRA, VMC ;
ALMEIDA, LM .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1994, 315 (01) :161-169
[8]   Anthocyanin antioxidants from edible fruits [J].
Einbond, LS ;
Reynertson, KA ;
Luo, XD ;
Basile, MJ ;
Kennelly, EJ .
FOOD CHEMISTRY, 2004, 84 (01) :23-28
[9]   INHIBITION OF OXIDATION OF HUMAN LOW-DENSITY-LIPOPROTEIN BY PHENOLIC SUBSTANCES IN RED WINE [J].
FRANKEL, EN ;
KANNER, J ;
GERMAN, JB ;
PARKS, E ;
KINSELLA, JE .
LANCET, 1993, 341 (8843) :454-457
[10]   DIET, AGING, AND CANCER [J].
GOODWIN, JS ;
BRODWICK, M .
CLINICS IN GERIATRIC MEDICINE, 1995, 11 (04) :577-&
123456