New insights into the function of IAP proteins: Modulation of the MYC/MAX/MAD network

被引：1
|
作者：
Wright, Casey W. [1 ]
Duckett, Colin S. [1 ,2 ]
机构：
[1] Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Sch Med, Dept Internal Med, Ann Arbor, MI 48109 USA
来源：
DEVELOPMENTAL CELL | 2008年 / 14卷 / 01期
关键词：
D O I：
10.1016/j.devcel.2007.12.015
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A growing number of studies have revealed that the inhibitor of apoptosis (IAP) proteins play a variety of cellular roles in addition to suppression of apoptosis. A recent study in Moiecular Cell demonstrates that one IAP member, c-IAP1, functions to potentiate the activity of Myc by triggering the ubiquitination and proteasomal degradation of the Myc inhibitory protein Mad1.
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页码：3 / 4
页数：2
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