Epilepsy and Pregnancy: For healthy pregnancies and happy outcomes. Suggestions for service improvements from the Multispecialty UK Epilepsy Mortality Group

被引：20

作者：

Leach, J. P. ^{[1
]}

Smith, P. E. ^{[12
]}

Craig, J. ^{[5
]}

Bagary, M. ^{[4
]}

Cavanagh, D. ^{[2
]}

Duncan, S. ^{[6
]}

Kelso, A. R. C. ^{[7
]}

Marson, A. G. ^{[3
]}

McCorry, D. ^{[8
]}

Nashef, L. ^{[9
]}

Nelson-Piercy, C. ^{[10
]}

Northridge, R. ^{[11
]}

Sieradzan, K. ^{[13
]}

Thangaratinam, S. ^{[14
]}

Walker, M. ^{[15
]}

Winterbottom, J. ^{[16
]}

Reuber, M. ^{[2
]}

机构：

[1] Univ Glasgow, Sch Med, Glasgow G12 8QQ, Lanark, Scotland

[2] Univ Sheffield, Royal Hallamshire Hosp, Acad Neurol Unit, Sheffield S2 1JF, S Yorkshire, England

[3] Univ Liverpool, Walton Ctr Neurol & Neurosurg, Dept Neurol, Liverpool L9 7LJ, Merseyside, England

[4] Barberry, Reg Complex Epilepsy Serv, 25 Vincent Dr, Birmingham B15 2FG, W Midlands, England

[5] Royal Victoria Hosp, Dept Neurol, Grosvenor Rd, Belfast BT12 6BA, Antrim, North Ireland

[6] Western Gen Hosp, Dept Clin Neurosci, Edinburgh EH4 2XU, Midlothian, Scotland

[7] Royal London Hosp, Whitechapel Rd, London E1 1BB, England

[8] Univ Hosp Birmingham, New Queen Elizabeth Hosp Birmingham, Birmingham B15 2WB, W Midlands, England

[9] Kings Coll Hosp London, Dept Neurol, London, England

[10] St Thomas Hosp, Womens Hlth Directorate, London SE1 7EH, England

[11] Ninewells Hosp, Dundee DD1 9SY, Scotland

[12] Univ Wales Hosp, Dept Neurol, Alan Richens Epilepsy Unit, Cardiff CF14 4XW, S Glam, Wales

[13] Southmead Hosp, Dept Neurol, Brunel Bldg,Level 2,Gate 3, Bristol BS10 5NB, Avon, England

[14] Queen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst, Maternal & Perinatal Hlth Womens Hlth Res Unit, London, England

[15] UCL Inst Neurol, Queen Sq, London WC1N 3BG, England

[16] Walton Ctr NHS Fdn Trust, Liverpool L9 7LJ, Merseyside, England

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2017年 / 50卷

关键词：

epilepsy; SUDEP; mortality; pregnancy; REFRACTORY EPILEPSY; DRUG; WOMEN;

D O I：

10.1016/j.seizure.2017.05.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Between 2009 and 2012 there were 26 epilepsy-related deaths in the UK of women who were pregnant or in the first post-partum year. The number of pregnancy-related deaths in women with epilepsy (WWE) has been increasing. Expert assessment suggests that most epilepsy-related deaths in pregnancy were preventable and attributable to poor seizure control. While prevention of seizures during pregnancy is important, a balance must be struck between seizure control and the teratogenic potential of antiepileptic drugs (AED5). A range of professional guidance on the management of epilepsy in pregnancy has previously been issued, but little attention has been paid to how optimal care can be delivered to WWE by a range of healthcare professionals. We summarise the findings of a multidisciplinary meeting with representation from a wide group of professional bodies. This focussed on the implementation of optimal pregnancy epilepsy care aiming to reduce mortality of epilepsy in mothers and reduce morbidity in babies exposed to AEDs in utero. We identify in particular -What stage to intervene -Golden Moments of opportunities for improving outcomes -Which Key Groups have a role in making change -When - 2020 vision of what these improvements aim to achieve. -How to monitor the success in this field We believe that the service improvement ideas developed for the UK may provide a template for similar initiatives in other countries. (C) 2017 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

引用

页码：67 / 72

页数：6

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