Surface Heparinization of Poly(ether ether ketone)

被引:0
作者
Sun Hui [1 ]
Chen Rui-chao [1 ]
Liu Shu [1 ]
Xu Guo-zhi [1 ]
机构
[1] Beijing Technol & Business Univ, Dept Mat & Mech Engn, Beijing 100048, Peoples R China
关键词
Poly(ether ether ketone)(PEEK); UV-Grafting; Space arm; Heparin immobilization; SINTERED POLYETHERETHERKETONE COMPOSITES; PLASMA; IMMOBILIZATION; FILMS; ADSORPTION; MEMBRANES;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Photo-grafting of hydrophilic monomer and space arms was used to enhance the hydrophilicity of poly(ether ether ketone)(PEEK) with the aim of extending its application to biological fields. PEEK films were surface modified by UV grafting of acrylic acid(AA) to introduce -COOH on PEEK surface. Adipic amine was used as a space arm to introduce heparin on PEEK surface based on the condensation reaction between -NH2 and -COOH. The modified PEEK(PEEK-COOH, PEEK-NH2 and PEEK-Hep) was characterized by energy-disperse spectroscopy (EDS), X-ray photoelectron spectroscopy(XPS) and water contact angle measurements, which show that heparin was grafted on PEEK surface. The contact angles of modified PEEK films were lower than those of original films, demonstrating a significant improvement of surface hydrophilicity.
引用
收藏
页码:542 / 545
页数:4
相关论文
共 32 条
  • [11] Surface modification of PE porous membranes based on the strong adhesion of polydopamine and covalent immobilization of heparin
    Jiang, Jin-Hong
    Zhu, Li-Ping
    Li, Xiao-Lin
    Xu, You-Yi
    Zhu, Bao-Ku
    [J]. JOURNAL OF MEMBRANE SCIENCE, 2010, 364 (1-2) : 194 - 202
  • [12] Surface characterization and in vitro blood compatibility of poly(ethylene terephthalate) immobilized with insulin and/or heparin using plasma glow discharge
    Kim, YJ
    Kang, IK
    Huh, MW
    Yoon, SC
    [J]. BIOMATERIALS, 2000, 21 (02) : 121 - 130
  • [13] Kyomoto M., 2009, INTERFACES, V1, P537
  • [14] Self-initiated surface grafting with poly(2-methacryloyloxyethyl phosphorylcholine) on poly(ether-ether-ketone)
    Kyomoto, Masayuki
    Moro, Toru
    Takatori, Yoshio
    Kawaguchi, Hiroshi
    Nakamura, Kozo
    Ishihara, Kazuhiko
    [J]. BIOMATERIALS, 2010, 31 (06) : 1017 - 1024
  • [15] H2/NH3 Plasma-Grafting of PEEK-WC-PU Membrane to Improve their cyto-Compatibility with Hepatocytes
    Laera, Stefania
    Lopez, Linda C.
    De Bartolo, Loredana
    Morelli, Sabrina
    Salerno, Simona
    Piscioneri, Antonella
    Nardulli, Marina
    Gristina, Roberto
    d'Agostino, Riccardo
    Favia, Pietro
    [J]. PLASMA PROCESSES AND POLYMERS, 2009, 6 : S81 - S84
  • [16] Coimmobilization of heparin/fibronectin mixture on titanium surfaces and their blood compatibility
    Li, Guicai
    Zhang, Fengming
    Liao, Yuzhen
    Yang, Ping
    Huang, Nan
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2010, 81 (01) : 255 - 262
  • [17] Interfacial studies on the ozone and air-oxidation-modified carbon fiber reinforced PEEK composites
    Li, J.
    [J]. SURFACE AND INTERFACE ANALYSIS, 2009, 41 (04) : 310 - 315
  • [18] Marchand-Brynaert J, 1998, RRD POLYM SCI, V2, P335
  • [19] Comparison of haemocompatibility improvement of four polymeric biomaterials by two heparinization techniques
    Michanetzis, GPA
    Katsala, N
    Missirlis, YF
    [J]. BIOMATERIALS, 2003, 24 (04) : 677 - 688
  • [20] Fibronectin adsorption or and covalent grafting on chemically modified PEEK film surfaces
    Noiset, O
    Schneider, YJ
    Marchand-Brynaert, J
    [J]. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 1999, 10 (06) : 657 - 677