Iodine/Hydrogen Peroxide Promoted Intramolecular Oxidative C-O Bond Formation in Ethanol at Room Temperature: A Green Approach to 1,3-Oxazines

被引：35
作者：
Deb, Mohit L. [1 ]
Borpatra, Paran J. [1 ]
Saikia, Prakash J. [2 ]
Baruah, Pranjal K. [1 ]
机构：
[1] Gauhati Univ, Dept Appl Sci, GUIST, Gauhati 781014, Assam, India
[2] CSIR, Analyt Chem Div, NEIST, Jorhat 785006, Assam, India
来源：
SYNLETT | 2017年 / 28卷 / 04期
关键词：
iodine catalysis; aminoalkylnaphthols; aminooalkylphenols; cyclization; oxazines; DEHYDROGENATIVE-COUPLING REACTION; REVERSE-TRANSCRIPTASE INHIBITORS; LIGHT PHOTOREDOX CATALYSIS; H BOND; TERTIARY-AMINES; VISIBLE-LIGHT; METAL-FREE; MUSCARINIC RECEPTORS; EFFICIENT SYNTHESIS; HYDROGEN-PEROXIDE;
D O I：
10.1055/s-0036-1589717
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An I-2/H2O2-promoted intramolecular C-O bond-formation reaction of a variety of 1-(aminoalkyl)-2-naphthols or 2-(aminoalkyl) phenols to give the corresponding 1,3-oxazines was developed. The reaction is simple, atom-economic, and proceeds smoothly at room temperature under metal-free conditions in ethanol as solvent.
引用
收藏
页码：461 / 466
页数：6
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