Diversity, evolution and population dynamics of avian influenza viruses circulating in the live poultry markets in China

被引：25

作者：

Chen, Liang-Jun ^{[1
,2
]}

Lin, Xian-Dan ^{[3
]}

Tian, Jun-Hua ^{[4
]}

Liao, Yong ^{[5
]}

Ying, Xu-Hua ^{[6
]}

Shao, Jian-Wei ^{[2
]}

Yu, Bin ^{[4
]}

Guo, Jing-Jing ^{[1
,2
]}

Wang, Miao-Ruo ^{[7
]}

Peng, Ying ^{[4
]}

Shi, Mang ^{[2
,8
,9
]}

Holmes, Edward C. ^{[2
,8
,9
]}

Yang, Zhan-Qiu ^{[1
]}

Zhang, Yong-Zhen ^{[1
,2
]}

机构：

[1] Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Inst Med Virol, Wuhan 430071, Peoples R China

[2] Chinese Ctr Dis Control & Prevent, Natl Inst Communicable Dis Control & Prevent, Collaborat Innovat Ctr Diag & Treatment Infect Di, State Key Lab Infect Dis Prevent & Control, Beijing 102206, Peoples R China

[3] Wenzhou Ctr Dis Control & Prevent, Wenzhou 325001, Zhejiang, Peoples R China

[4] Wuhan Ctr Dis Control & Prevent, Wuhan 430015, Hubei Province, Peoples R China

[5] Ganzhou Ctr Dis Control & Prevent, Ganzhou 341000, Jiangxi, Peoples R China

[6] Yuhuan Ctr Dis Control & Prevent, Yuhuan 317600, Zhejiang, Peoples R China

[7] Longquan Ctr Dis Control & Prevent, Longquan, Zhejiang, Peoples R China

[8] Univ Sydney, Marie Bashir Inst Infect Dis & Biosecur, Sch Life & Environm Sci, Charles Perkins Ctr, Sydney, NSW 2006, Australia

[9] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia

来源：

VIROLOGY | 2017年 / 505卷

基金：

中国国家自然科学基金; 澳大利亚国家健康与医学研究理事会;

关键词：

Avian influenza virus; Live poultry markets; H5N6; virus; Reassortant; Evolution; A H5N6 VIRUS; HUMAN INFECTION; MAXIMUM-LIKELIHOOD; H7N9; VIRUS; TRANSMISSION; REASSORTANTS; EMERGENCE; H9N2; EPIDEMIOLOGY; VIRULENCE;

D O I：

10.1016/j.virol.2017.02.009

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Live poultry markets (LPMs) are an important source of novel avian influenza viruses (AIV). During 2015-2016 we surveyed AIV diversity in ten LPMs in Hubei, Zhejiang and Jiangxi provinces, China. A high diversity and prevalence of AIVs (totaling 12 subtypes) was observed in LPMs in these provinces. Strikingly, however, the subtypes discovered during 2015-2016 were markedly different to those reported by us in these same localities one year previously, suggesting a dynamic shift in viral genetic diversity over the course of a single year. Phylogenetic analyses revealed frequent reassortment, including between high and low pathogenic AIV subtypes and among those that circulate in domestic and wild birds. Notably, the novel H5N6 reassortant virus, which contains a set of H9N2-like internal genes, was prevalent in all three regions surveyed. Overall, these data highlight the profound changes in genetic diversity and in patterns of reassortment in those AIVs that circulate in LPMs.

引用

页码：33 / 41

页数：9

共 54 条

[1] An overview of the epidemiology of avian influenza [J].

Alexander, Dennis J. .

VACCINE, 2007, 25 (30) :5637-5644

[2] Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China [J].

Bi, Yuhai ;

Chen, Quanjiao ;

Wang, Qianli ;

Chen, Jianjun ;

Jin, Tao ;

Wong, Gary ;

Quan, Chuansong ;

Liu, Jun ;

Wu, Jun ;

Yin, Renfu ;

Zhao, Lihua ;

Li, Mingxin ;

Ding, Zhuang ;

Zou, Rongrong ;

Xu, Wen ;

Li, Hong ;

Wang, Huijun ;

Tian, Kegong ;

Fu, Guanghua ;

Huang, Yu ;

Shestopalov, Alexander ;

Li, Shoujun ;

Xu, Bing ;

Yu, Hongjie ;

Luo, Tingrong ;

Lu, Lin ;

Xu, Xun ;

Luo, Yang ;

Liu, Yingxia ;

Shi, Weifeng ;

Liu, Di ;

Gao, George Fu .

Cell Host & Microbe, 2016, 20 (06) :810-821

[3] Two novel reassortants of avian influenza A (H5N6) virus in China [J].

Bi, Yuhai ;

Mei, Kun ;

Shi, Weifeng ;

Liu, Di ;

Yu, Xiaolan ;

Gao, Zhimin ;

Zhao, Lihua ;

Gao, George F. ;

Chen, Jianjun ;

Chen, Quanjiao .

JOURNAL OF GENERAL VIROLOGY, 2015, 96 :975-981

[4] Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003 [J].

Butt, KM ;

Smith, GJD ;

Chen, HL ;

Zhang, LJ ;

Leung, YHC ;

Xu, KM ;

Lim, W ;

Webster, RG ;

Yuen, KY ;

Peiris, JSM ;

Guan, Y .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (11) :5760-5767

[5] Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection : a descriptive study [J].

Chen, HaiYing ;

Yuan, Hui ;

Gao, Rongbao ;

Zhang, Jinxiang ;

Wang, Dayan ;

Xiong, Ying ;

Fan, GuoYin ;

Yang, Fan ;

Li, Xiaodan ;

Zhou, Jianfang ;

Zou, Shumei ;

Yang, Lei ;

Chen, Tao ;

Dong, Libo ;

Bo, Hong ;

Zhao, Xiang ;

Zhang, Ye ;

Lan, Yu ;

Bai, Tian ;

Dong, Jie ;

Li, Qun ;

Wang, ShiWen ;

Zhang, YanPing ;

Li, Hui ;

Gong, Tian ;

Shi, Yong ;

Ni, Xiansheng ;

Li, Jianxiong ;

Zhou, Jun ;

Fan, Jiyi ;

Wu, Jingwen ;

Zhou, Xianfeng ;

Hu, Maohong ;

Wan, Jianguo ;

Yang, WeiZhong ;

Li, DeXin ;

Wu, Guizhen ;

Feng, ZiJian ;

Gao, George F. ;

Wang, Yu ;

Jin, Qi ;

Liu, Mingbin ;

Shu, Yuelong .

LANCET, 2014, 383 (9918) :714-721

[6] Diversity and evolution of avian influenza viruses in live poultry markets, free-range poultry and wild wetland birds in China [J].

Chen, Liang-Jun ;

Lin, Xian-Dan ;

Guo, Wen-Ping ;

Tian, Jun-Hua ;

Wang, Wen ;

Ying, Xu-Hua ;

Wang, Miao-Ruo ;

Yu, Bin ;

Yang, Zhan-Qiu ;

Shi, Mang ;

Holmes, Edward C. ;

Zhang, Yong-Zhen .

JOURNAL OF GENERAL VIROLOGY, 2016, 97 :844-854

[7] Live Animal Markets in Minnesota: A Potential Source for Emergence of Novel Influenza A Viruses and Interspecies Transmission [J].

Choi, Mary J. ;

Torremorell, Montserrat ;

Bender, Jeff B. ;

Smith, Kirk ;

Boxrud, David ;

Ertl, Jon R. ;

Yang, My ;

Suwannakarn, Kamol ;

Her, Duachi ;

Nguyen, Jennifer ;

Uyeki, Timothy M. ;

Levine, Min ;

Lindstrom, Stephen ;

Katz, Jacqueline M. ;

Jhung, Michael ;

Vetter, Sara ;

Wong, Karen K. ;

Sreevatsan, Srinand ;

Lynfield, Ruth .

CLINICAL INFECTIOUS DISEASES, 2015, 61 (09) :1355-1362

[8] Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus [J].

Claas, ECJ ;

Osterhaus, ADME ;

van Beek, R ;

De Jong, JC ;

Rimmelzwaan, GF ;

Senne, DA ;

Krauss, S ;

Shortridge, KF ;

Webster, RG .

LANCET, 1998, 351 (9101) :472-477

[9] Phylogenetic analysis and pathogenicity of H3 subtype avian influenza viruses isolated from live poultry markets in China [J].

Cui, Hongrui ;

Shi, Ying ;

Ruan, Tao ;

Li, Xuesong ;

Teng, Qiaoyang ;

Chen, Hongjun ;

Yang, Jianmei ;

Liu, Qinfang ;

Li, Zejun .

SCIENTIFIC REPORTS, 2016, 6

[10] Sustained live poultry market surveillance contributes to early warnings for human infection with avian influenza viruses [J].

Fang, Shisong ;

Bai, Tian ;

Yang, Lei ;

Wang, Xin ;

Peng, Bo ;

Liu, Hui ;

Geng, Yijie ;

Zhang, Renli ;

Ma, Hanwu ;

Zhu, Wenfei ;

Wang, Dayan ;

Cheng, Jinquan ;

Shu, Yuelong .

EMERGING MICROBES & INFECTIONS, 2016, 5

← 1 2 3 4 5 6 →