Effects of ocean acidification on immune responses of the Pacific oyster Crassostrea gigas

被引：125

作者：

Wang, Qing ^{[1
]}

Cao, Ruiwen ^{[1
,4
]}

Ning, Xuanxuan ^{[2
]}

You, Liping ^{[1
]}

Mu, Changkao ^{[3
]}

Wang, Chunlin ^{[3
]}

Wei, Lei ^{[1
]}

Cong, Ming ^{[1
]}

Wu, Huifeng ^{[1
]}

Zhao, Jianmin ^{[1
]}

机构：

[1] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China

[2] SOA, Yantai Ocean Environm Monitoring Cent Stn, Yantai 264006, Peoples R China

[3] Ningbo Univ, Fac Life Sci & Biotechnol, Minist Educ, Key Lab Appl Marine Biotechnol, Ningbo 315211, Zhejiang, Peoples R China

[4] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

FISH & SHELLFISH IMMUNOLOGY | 2016年 / 49卷

基金：

中国国家自然科学基金;

关键词：

Ocean acidification; pCO(2); Oyster; Immune response; Antioxidant enzyme; OXIDATIVE-STRESS; CLIMATE-CHANGE; BIOMARKERS; ORGANISMS; APOPTOSIS; VIRGINICA; DEFENSES; SEAWATER; CADMIUM; IMPACT;

D O I：

10.1016/j.fsi.2015.12.025

中图分类号：

S9 [水产、渔业];

学科分类号：

0908 ;

摘要：

Ocean acidification (OA), caused by anthropogenic CO(2)emissions, has been proposed as one of the greatest threats in marine ecosystems. A growing body of evidence shows that ocean acidification can impact development, survival, growth and physiology of marine calcifiers. In this study, the immune responses of the Pacific oyster Crassostrea gigas were investigated after elevated pCO(2) exposure for 28 days. The results demonstrated that OA caused an increase of apoptosis and reactive oxygen species (ROS) production in hemocytes. Moreover, elevated pCO(2) had an inhibitory effect on some antioxidant enzyme activities and decreased the GSH level in digestive gland. However, the mRNA expression pattern of several immune related genes varied depending on the exposure time and tissues. After exposure to pCO(2) at 2000 ppm for 28 days, the mRNA expressions of almost all tested genes were significantly suppressed in gills and stimulated in hemocytes. Above all, our study demonstrated that elevated pCO(2) have a significant impact on the immune systems of the Pacific oyster, which may constitute as a potential threat to increased susceptibility of bivalves to diseases. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：24 / 33

页数：10

共 45 条

[1] Moderate acidification affects growth but not survival of 6-month-old oysters [J].