Correlation between angiographic transit times and neurological status on admission in patients with aneurysmal subarachnoid hemorrhage

被引:14
作者
Ivanov, Alexander [1 ]
Linninger, Andreas [1 ,2 ]
Hsu, Chih-Yang [2 ]
Amin-Hanjani, Sepideh [1 ]
Aletich, Victor A. [1 ]
Charbel, Fady T. [1 ]
Alaraj, Ali [1 ]
机构
[1] Univ Illinois, Dept Neurosurg, Chicago, IL USA
[2] Univ Illinois, Dept Bioengn, Chicago, IL USA
关键词
digital subtraction angiography; transit times; subarachnoid hemorrhage; Hunt and Hess; neurological outcome; vascular disorders; DIGITAL-SUBTRACTION-ANGIOGRAPHY; MAGNETIC-RESONANCE ANGIOGRAPHY; CEREBRAL-BLOOD-FLOW; INTRACRANIAL ANEURYSMS; COMPUTED-TOMOGRAPHY; VASOSPASM; OXYGEN; MODEL; RISK; RAT;
D O I
10.3171/2015.4.JNS15134
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
OBJECTIVE The use of digital subtraction angiography (DSA) for semiquantitative cerebral blood flow (CBF) assessment is a new technique. The aim of this study was to determine whether patients with aneurysmal subarachnoid hemorrhage (aSAH) with higher Hunt and Hess grades also had higher angiographic contrast transit times (TTs) than patients with lower grades. METHODS A cohort of 30 patients with aSAH and 10 patients without aSAH was included. Relevant clinical information was collected. A method to measure DSA TTs by color-coding reconstructions from DSA contrast-intensity images was applied. Regions of interest (ROIs) were chosen over major cerebral vessels. The estimated TTs included time-to-peak, from 0% to 100% (TTP0-100), TTP from 25% to 100% (TTP25-100), and TT from 100% to 10% (TT100-10) contrast intensities. Statistical analysis was used to compare TTs between Group A (Hunt and Hess Grade I-II), Group B (Hunt and Hess Grade III-IV), and the control group. The correlation coefficient was calculated between different ROIs in aSAH groups. RESULTS There was no difference in demographic factors between Group A (n = 10), Group B (n = 20), and the control group (n =10). There was a strong correlation in all TTs between ROIs in the middle cerebral artery (M-1, M-2) and anterior cerebral artery (A(1), A(2)). There was a statistically significant difference between Groups A and B in all TT parameters for ROIs. TT100-10 values in the control group were significantly lower than the values in Group B. CONCLUSIONS The DSA TTs showed significant correlation with Hunt and Hess grades. TT delays appear to be independent of increased intracranial pressure and may be an indicator of decreased CBF in patients with a higher Hunt and Hess grade. This method may serve as an indirect technique to assess relative CBF in the angiography suite.
引用
收藏
页码:1093 / 1099
页数:7
相关论文
共 38 条
[1]   Use of quantitative magnetic resonance angiography to stratify stroke risk in symptomatic vertebrobasilar disease [J].
Amin-Hanjani, S ;
Du, XJ ;
Zhao, MD ;
Walsh, K ;
Malisch, TW ;
Charbel, FT .
STROKE, 2005, 36 (06) :1140-1145
[2]   Vertebrobasilar Flow Evaluation and Risk of Transient Ischaemic Attack and Stroke study (VERiTAS): rationale and design [J].
Amin-Hanjani, Sepideh ;
Rose-Finnell, Linda ;
Richardson, DeJuran ;
Ruland, Sean ;
Pandey, Dilip ;
Thulborn, Keith R. ;
Liebeskind, David S. ;
Zipfel, Gregory J. ;
Elkind, Mitchell S. V. ;
Kramer, Jeffrey ;
Silver, Frank L. ;
Kasner, Scott E. ;
Caplan, Louis R. ;
Derdeyn, Colin P. ;
Gorelick, Philip B. ;
Charbel, Fady T. .
INTERNATIONAL JOURNAL OF STROKE, 2010, 5 (06) :499-505
[3]   Detection of Intracranial In-Stent Restenosis Using Quantitative Magnetic Resonance Angiography [J].
Amin-Hanjani, Sepideh ;
Alaraj, Ali ;
Calderon-Arnulphi, Mateo ;
Aletich, Victor A. ;
Thulborn, Keith R. ;
Charbel, Fady T. .
STROKE, 2010, 41 (11) :2534-2538
[4]   Acute vasoconstriction after subarachnoid hemorrhage [J].
Bederson, JB ;
Levy, AL ;
Ding, WH ;
Kahn, R ;
DiPerna, CA ;
Jenkins, AL III ;
Vallabhajosyula, P .
NEUROSURGERY, 1998, 42 (02) :352-360
[5]   CORTICAL BLOOD-FLOW AND CEREBRAL PERFUSION-PRESSURE IN A NEW NONCRANIOTOMY MODEL OF SUBARACHNOID HEMORRHAGE IN THE RAT [J].
BEDERSON, JB ;
GERMANO, IM ;
GUARINO, L .
STROKE, 1995, 26 (06) :1086-1091
[6]  
Binaghi S, 2007, AM J NEURORADIOL, V28, P750
[7]   Risk factors and outcome in 100 patients with aneurysmal subarachnoid hemorrhage [J].
Bonilha, L ;
Marques, EL ;
Carelli, EF ;
Fernandes, YB ;
Cardoso, AC ;
Maldaum, MVM ;
Borges, G .
ARQUIVOS DE NEURO-PSIQUIATRIA, 2001, 59 (3B) :676-680
[8]   Mechanisms of early brain injury after subarachnoid hemorrhage (vol 26, pg 1341, 2006) [J].
Cahill, Julian ;
Calvert, John W. ;
Zhang, John H. .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2006, 26 (11) :1463-1463
[9]   In Vivo Evaluation of Quantitative MR Angiography in a Canine Carotid Artery Stenosis Model [J].
Calderon-Arnulphi, M. ;
Amin-Hanjani, S. ;
Alaraj, A. ;
Zhao, M. ;
Du, X. ;
Ruland, S. ;
Zhou, X. J. ;
Thulborn, K. R. ;
Charbel, F. T. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2011, 32 (08) :1552-1559
[10]   CEREBRAL OXYGEN-METABOLISM AFTER ANEURYSMAL SUBARACHNOID HEMORRHAGE [J].
CARPENTER, DA ;
GRUBB, RL ;
TEMPEL, LW ;
POWERS, WJ .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1991, 11 (05) :837-844