Potassium Fluoride-Modified Clay as a Reusable Heterogeneous Catalyst for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones

被引：17

作者：

Bentahar, S. ^{[1
]}

Taleb, M. Ait ^{[2
]}

Sabour, A. ^{[1
]}

Dbik, A. ^{[1
]}

El Khomri, M. ^{[1
]}

El Messaoudi, N. ^{[1
]}

Lacherai, A. ^{[1
]}

Mamouni, R. ^{[2
]}

机构：

[1] Ibn Zohr Univ, Fac Sci, Dept Chem, Lab Appl Chem & Environm, Agadir, Morocco

[2] Ibn Zohr Univ, Dept Chem, Fac Sci, Team Mat Catalysis & Valorizat Nat Resources, Agadir, Morocco

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 55卷 / 09期

关键词：

KF-modified clay; heterogeneous catalysts; Biginelli reaction; substituted pyrimidines; 3; 4-dihy-dropyrimidin-2(1H)-ones; BIGINELLI REACTION; IMPROVED PROTOCOL; HIGHLY EFFICIENT; HETEROPOLY ACID; GREEN SYNTHESIS; DIHYDROPYRIMIDINONES; MILD;

D O I：

10.1134/S1070428019090240

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Potassium fluoride-modified clay collected from the region of Agadir (Morocco) was used as a hetaerogeneous catalyst in the one-pot synthesis of 3,4-dihydropyrimidine-2(1H)-one derivatives via the Biginelli reaction. The products were obtained with excellent yields (88-98%). The catalyst was characterized X-ray powder diffraction, Fourier-transform IR spectroscopy, scanning electron microscopy, differential thermal analysis, thermogravimetry, and Brunauer-Emmett-Teller (BET) analysis. Plausible reaction mechanisms for both reactions have been proposed. The catalyst can be recycled five times without loss of catalytic activity.

引用

页码：1423 / 1431

页数：9

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