Human genomics: The genome finishers

被引:10
作者
Dolgin, Elie
机构
关键词
COMMON INVERSION; ANNOTATION; SEQUENCE;
D O I
10.1038/462843a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Dedicated scientists are working hard to close the gaps, fix the errors and finally complete the human genome sequence. Elie Dolgin looks at how close they are.
引用
收藏
页码:843 / 845
页数:3
相关论文
共 11 条
[1]   Finishing the euchromatic sequence of the human genome [J].
Collins, FS ;
Lander, ES ;
Rogers, J ;
Waterston, RH .
NATURE, 2004, 431 (7011) :931-945
[2]   A vision for the future of genomics research [J].
Collins, FS ;
Green, ED ;
Guttmacher, AE ;
Guyer, MS .
NATURE, 2003, 422 (6934) :835-847
[3]   Closing gaps in the human genome using sequencing by synthesis [J].
Garber, Manuel ;
Zody, Michael C. ;
Arachchi, Harindra M. ;
Berlin, Aaron ;
Gnerre, Sante ;
Green, Lisa M. ;
Lennon, Niall ;
Nusbaum, Chad .
GENOME BIOLOGY, 2009, 10 (06)
[4]   The DNA sequence and biological annotation of human chromosome 1 [J].
Gregory, SG ;
Barlow, KF ;
Mclay, KE ;
Kaul, R ;
Swarbreck, D ;
Dunham, A ;
Scott, CE ;
Howe, KL ;
Woodfine, K ;
Spencer, CCA ;
Jones, MC ;
Gillson, C ;
Searle, S ;
Zhou, Y ;
Kokocinski, F ;
McDonald, L ;
Evans, R ;
Phillips, K ;
Atkinson, A ;
Cooper, R ;
Jones, C ;
Hall, RE ;
Andrews, TD ;
Lloyd, C ;
Ainscough, R ;
Almeida, JP ;
Ambrose, KD ;
Anderson, F ;
Andrew, RW ;
Ashwell, RIS ;
Aubin, K ;
Babbage, AK ;
Bagguley, CL ;
Bailey, J ;
Beasley, H ;
Bethel, G ;
Bird, CP ;
Bray-Allen, S ;
Brown, JY ;
Brown, AJ ;
Buckley, D ;
Burton, J ;
Bye, J ;
Carder, C ;
Chapman, JC ;
Clark, SY ;
Clarke, G ;
Clee, C ;
Cobley, V ;
Collier, RE .
NATURE, 2006, 441 (7091) :315-321
[5]   Variation analysis and gene annotation of eight MHC haplotypes: The MHC haplotype project [J].
Horton, Roger ;
Gibson, Richard ;
Coggill, Penny ;
Miretti, Marcos ;
Allcock, Richard J. ;
Almeida, Jeff ;
Forbes, Simon ;
Gilbert, James G. R. ;
Halls, Karen ;
Harrow, Jennifer L. ;
Hart, Elizabeth ;
Howe, Kevin ;
Jackson, David K. ;
Palmer, Sophie ;
Roberts, Anne N. ;
Sims, Sarah ;
Stewart, C. Andrew ;
Traherne, James A. ;
Trevanion, Steve ;
Wilming, Laurens ;
Rogers, Jane ;
de Jong, Pieter J. ;
Elliott, John F. ;
Sawcer, Stephen ;
Todd, John A. ;
Trowsdale, John ;
Beck, Stephan .
IMMUNOGENETICS, 2008, 60 (01) :1-18
[6]   A new chromosome 17q21.31 microdeletion syndrome associated with a common inversion polymorphism [J].
Koolen, David A. ;
Vissers, Lisenka E. L. M. ;
Pfundt, Rolph ;
de Leeuw, Nicole ;
Knight, Samantha J. L. ;
Regan, Regina ;
Kooy, R. Frank ;
Reyniers, Edwin ;
Romano, Corrado ;
Fichera, Marco ;
Schinzel, Albert ;
Baumer, Alessandra ;
Anderlid, Britt-Marie ;
Schoumans, Jacqueline ;
Knoers, Nine V. ;
van Kessel, Ad Geurts ;
Sistermans, Erik A. ;
Veltman, Joris A. ;
Brunner, Han G. ;
de Vries, Bert B. A. .
NATURE GENETICS, 2006, 38 (09) :999-1001
[7]   Initial sequencing and analysis of the human genome [J].
Lander, ES ;
Int Human Genome Sequencing Consortium ;
Linton, LM ;
Birren, B ;
Nusbaum, C ;
Zody, MC ;
Baldwin, J ;
Devon, K ;
Dewar, K ;
Doyle, M ;
FitzHugh, W ;
Funke, R ;
Gage, D ;
Harris, K ;
Heaford, A ;
Howland, J ;
Kann, L ;
Lehoczky, J ;
LeVine, R ;
McEwan, P ;
McKernan, K ;
Meldrim, J ;
Mesirov, JP ;
Miranda, C ;
Morris, W ;
Naylor, J ;
Raymond, C ;
Rosetti, M ;
Santos, R ;
Sheridan, A ;
Sougnez, C ;
Stange-Thomann, N ;
Stojanovic, N ;
Subramanian, A ;
Wyman, D ;
Rogers, J ;
Sulston, J ;
Ainscough, R ;
Beck, S ;
Bentley, D ;
Burton, J ;
Clee, C ;
Carter, N ;
Coulson, A ;
Deadman, R ;
Deloukas, P ;
Dunham, A ;
Dunham, I ;
Durbin, R ;
French, L .
NATURE, 2001, 409 (6822) :860-921
[8]   Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome [J].
Sharp, Andrew J. ;
Hansen, Sierra ;
Selzer, Rebecca R. ;
Cheng, Ze ;
Regan, Regina ;
Hurst, Jane A. ;
Stewart, Helen ;
Price, Sue M. ;
Blair, Edward ;
Hennekam, Raoul C. ;
Fitzpatrick, Carrie A. ;
Segraves, Rick ;
Richmond, Todd A. ;
Guiver, Cheryl ;
Albertson, Donna G. ;
Pinkel, Daniel ;
Eis, Peggy S. ;
Schwartz, Stuart ;
Knight, Samantha J. L. ;
Eichler, Evan E. .
NATURE GENETICS, 2006, 38 (09) :1038-1042
[9]   Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability [J].
Shaw-Smith, Charles ;
Pittman, Alan M. ;
Willatt, Lionel ;
Martin, Howard ;
Rickman, Lisa ;
Gribble, Susan ;
Curley, Rebecca ;
Cumming, Sally ;
Dunn, Carolyn ;
Kalaitzopoulos, Dimitrios ;
Porter, Keith ;
Prigmore, Elena ;
Krepischi-Santos, Ana C. V. ;
Varela, Monica C. ;
Koiffmann, Celia P. ;
Lees, Andrew J. ;
Rosenberg, Carla ;
Firth, Helen V. ;
de Silva, Rohan ;
Carter, Nigel P. .
NATURE GENETICS, 2006, 38 (09) :1032-1037
[10]   A common inversion under selection in Europeans [J].
Stefansson, H ;
Helgason, A ;
Thorleifsson, G ;
Steinthorsdottir, V ;
Masson, G ;
Barnard, J ;
Baker, A ;
Jonasdottir, A ;
Ingason, A ;
Gudnadottir, VG ;
Desnica, N ;
Hicks, A ;
Gylfason, A ;
Gudbjartsson, DF ;
Jonsdottir, GM ;
Sainz, J ;
Agnarsson, K ;
Birgisdottir, B ;
Ghosh, S ;
Olafsdottir, A ;
Cazier, JB ;
Kristjansson, K ;
Frigge, ML ;
Thorgeirsson, TE ;
Gulcher, JR ;
Kong, A ;
Stefansson, K .
NATURE GENETICS, 2005, 37 (02) :129-137