Cardiovascular Disease Prevention in Men with Vascular Erectile Dysfunction: The View of the Preventive Cardiologist

被引:44
作者
Shah, Nishant P. [1 ]
Cainzos-Achirica, Miguel [1 ,2 ,3 ]
Feldman, David I. [1 ]
Blumenthal, Roger S. [1 ]
Nasir, Khurram [1 ,4 ]
Miner, Martin M. [5 ,6 ]
Billups, Kevin L. [1 ,7 ]
Blaha, Michael J. [1 ]
机构
[1] Johns Hopkins Med Inst, Ciccarone Ctr Prevent Heart Dis, Dept Cardiol, Baltimore, MD 21205 USA
[2] Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD USA
[3] Johns Hopkins Univ, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA
[4] Baptist Hlth South Florida, Miami, FL USA
[5] Miriam Hosp, Dept Family Med, Providence, RI 02906 USA
[6] Brown Univ, Providence, RI 02912 USA
[7] Johns Hopkins Univ Hosp, James Buchanan Brady Urol Inst, Baltimore, MD 21287 USA
关键词
Atherosclerosis; Cardiovascular disease; Coronary artery calcium; Erectile dysfunction; Prevention; Risk; Vascular erectile dysfunction; CORONARY-ARTERY CALCIUM; INTIMA-MEDIA THICKNESS; ANKLE-BRACHIAL INDEX; ASSOCIATION TASK-FORCE; ALL-CAUSE MORTALITY; C-REACTIVE PROTEIN; HEART-DISEASE; RISK-FACTORS; ENDOTHELIAL DYSFUNCTION; ASYMPTOMATIC ADULTS;
D O I
10.1016/j.amjmed.2015.08.038
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Vascular erectile dysfunction is a powerful marker of increased cardiovascular risk. However, current guidelines lack specific recommendations on the role that the evaluation of vascular erectile dysfunction should play in cardiovascular risk assessment, as well on the risk stratification strategy that men with vascular erectile dysfunction should undergo. In the last 3 years, erectile dysfunction experts have made a call for more specific guidance and have proposed the selective use of several prognostic tests for further cardiovascular risk assessment in these patients. Among them, stress testing has been prioritized, whereas other tests are considered second-line tools. In this review, we provide additional perspective from the viewpoint of the preventive cardiologist. We discuss the limitations of current risk scores and the potential interplay between erectile dysfunction assessment and the use of personalized prognostic tools, such as the coronary artery calcium score, in the cardiovascular risk stratification and management of men with vascular erectile dysfunction. Finally, we present an algorithm for primary care physicians, urologists, and cardiologists to aid clinical decision-making. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:251 / 259
页数:9
相关论文
共 92 条
[1]   Preventing myocardial infarction in the young adult in the first place: How do the National Cholesterol Education Panel III guidelines perform? [J].
Akosah, KO ;
Schaper, A ;
Cogbill, C ;
Schoenfeld, P .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (09) :1475-1479
[2]   Mild hypercholesterolemia and premature heart disease: Do the national criteria underestimate disease risk? [J].
Akosah, KO ;
Gower, E ;
Groon, L ;
Rooney, BL ;
Schaper, A .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 35 (05) :1178-1184
[3]   Traditional cardiovascular disease risk factors associated with one-year all-cause mortality among those with coronary artery calcium scores ≥400 [J].
Al Rifai, Mahmoud ;
McEvoy, John W. ;
Nasir, Khurram ;
Rumberger, Jon ;
Feldman, David ;
Budoff, Matthew J. ;
Blaha, Michael J. .
ATHEROSCLEROSIS, 2015, 241 (02) :495-497
[4]   Does Erectile Dysfunction Contribute to Cardiovascular Disease Risk Prediction Beyond the Framingham Risk Score? [J].
Araujo, Andre B. ;
Hall, Susan A. ;
Ganz, Peter ;
Chiu, Gretchen R. ;
Rosen, Raymond C. ;
Kupelian, Varant ;
Travison, Thomas G. ;
McKinlay, John B. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 55 (04) :350-356
[5]  
Aytac IA, 1999, BJU INT, V84, P50
[6]  
Bivalacqua TJ, 2003, J ANDROL, V24, pS17
[7]   Modelling the decreasing coronary heart disease mortality in Sweden between 1986 and 2002 [J].
Bjorck, Lena ;
Rosengren, Annika ;
Bennett, Kathleen ;
Lappas, George ;
Capewell, Simon .
EUROPEAN HEART JOURNAL, 2009, 30 (09) :1046-1056
[8]   Absence of Coronary Artery Calcification and All-Cause Mortality [J].
Blaha, Michael ;
Budoff, Matthew J. ;
Shaw, Leslee J. ;
Khosa, Faisal ;
Rumberger, John A. ;
Berman, Daniel ;
Callister, Tracy ;
Raggi, Paolo ;
Blumenthal, Roger S. ;
Nasir, Khurram .
JACC-CARDIOVASCULAR IMAGING, 2009, 2 (06) :692-700
[9]   The new "intermediate risk" group: A comparative analysis of the new 2013 ACC/AHA risk assessment guidelines versus prior guidelines in men [J].
Blaha, Michael J. ;
Dardari, Zeina A. ;
Blumenthal, Roger S. ;
Martin, Seth S. ;
Nasir, Khurram ;
Al-Mallah, Mouaz H. .
ATHEROSCLEROSIS, 2014, 237 (01) :1-4
[10]   New risk-assessment guidelines-more or less personalized? [J].
Blaha, Michael J. ;
Blumenthal, Roger S. .
NATURE REVIEWS CARDIOLOGY, 2014, 11 (03) :136-137