Effect of Ag, Cu, and ZnO Nanoparticle Suspensions on the Antimicrobial Activity of Tribulus Terrestris Herbal Extracts

The antimicrobial growth inhibition and mechanistic activities of silver (Ag NPs), zinc oxide (ZnO NPs), and copper (Cu NPs) nanoparticles were investigated in presence of medicinal plant extracts of Tribulus Terrestris. The extract in different concentrations (5, 10, 20, and 30%) along with selected nanoparticles suspension mixture was used for antimicrobial activity testing against some human pathogenic microorganisms. Among the tested bacterial strains, Escherichia coli and Proteus sp were the most susceptible at 30% concentration followed by a moderate activity against Morganella sp, Entrococcus Faecalis, Staphylococcus aureus, and Candida albicans. Tribulus Terrestris had no effect on Acetobacter sp and Streptococcus agalactia. The used nanoparticles in the present investigation have shown excellent antimicrobial activity in the presence of Tribulus Terrestris, hence they can be used as potent sources for antibacterial agents.