Anti-inflammatory secondary metabolites from the stems of Millettia dielsiana Harms ex Diels

被引：24

作者：

Le Duc Dat ^{[1
,2
]}

Nguyen Thi Minh Tu ^{[7
]}

Ngo Viet Duc ^{[2
]}

Bui Thi Thuy Luyen ^{[5
]}

Chu Thi Thanh Huyen ^{[5
]}

Jang, Hyun Jae ^{[6
]}

Dang Thi Thu ^{[7
]}

Tran Thu Huong ^{[8
]}

Le Huyen Tram ^{[8
]}

Nguyen Van Thong ^{[8
]}

Nguyen Duc Hung ^{[9
]}

Young Ho Kim ^{[4
]}

Nguyen Phuong Thao ^{[3
]}

机构：

[1] Ton Duc Thang Univ, Inst Computat Sci, Div Computat Phys, Ho Chi Minh City, Vietnam

[2] Ton Duc Thang Univ, Fac Pharm, Ho Chi Minh City, Vietnam

[3] VAST, Inst Marine Biochem, 18 Hoang Quoc Viet, Hanoi, Vietnam

[4] Chungnam Natl Univ, Coll Pharm, Daejeon 34134, South Korea

[5] Hanoi Univ Pharm, 13-15 Le Thanh Tong, Hanoi, Vietnam

[6] Korea Res Inst Biosci & Biotechnol, Immmoregulatory Mat Res Ctr, Jeonbuk 56212, South Korea

[7] Hanoi Univ Sci & Technol, Sch Biotechnol & Food Technol, Hanoi, Vietnam

[8] Hanoi Univ Sci & Technol, Sch Chem Engn, Hanoi, Vietnam

[9] Phutho Coll Med & Pharm, Ctr Drug Res & Technol Transfer, Viettri City, Phutho Province, Vietnam

来源：

CARBOHYDRATE RESEARCH | 2019年 / 484卷

基金：

新加坡国家研究基金会;

关键词：

Millettia dielsiana; Leguminosae; Mildiside A; Phenolic compound; Anti-inflammatory effect; NITRIC-OXIDE; IDENTIFICATION; CONSTITUENTS; FLAVONOIDS; GLYCOSIDES; ROOTS; BIOACTIVITY; INHIBITION; LEAVES;

D O I：

10.1016/j.carres.2019.107778

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A phytochemical investigation for the constituents of the stems of Millettia dielsiana Harms ex Diels resulted in the isolation of a new isoflavone glycoside, mildiside A (1), and 14 known compounds (2-15). Their chemical structures were determined using a combination of IR, NMR, MS, and optical rotation analysis, as well as comparison with the literature data. The ethanolic (EtOH) extract and several isolated compounds exert the inflammatory effect of nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cells.

引用

页数：5

共 36 条

[1] Amani S.A., 2012, PHYTOTHER RES, V27, P126
[2] Banzouzi J. T., 2008, International Journal of Botany, V4, P406
[3] Chemical constituents and coagulation activity of Agastache rugosa
Cao, Pengran
Xie, Pingyao
Wang, Xuebiao
Wang, Jinmei
Wei, Jinfeng
Kang, Wen-yi
[J]. BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2017, 17
[4] CARMICHAEL J, 1987, CANCER RES, V47, P943
[5] Inhibition of Nitric Oxide (NO) Production in Lipopolysaccharide (LPS)-Activated Murine Macrophage RAW 264.7 Cells by the Norsesterterpene Peroxide, Epimuqubilin A
Cheenpracha, Sarot
Park, Eun-Jung
Rostama, Bahman
Pezzuto, John M.
Chang, Leng Chee
[J]. MARINE DRUGS, 2010, 8 (03): : 429 - 437
[6] Chen Y P, 1986, Prog Clin Biol Res, V213, P297
[7] Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis
Deyou, Tsegaye
Gumula, Ivan
Pang, Fangfang
Gruhonjic, Amra
Mumo, Michael
Holleran, John
Duffy, Sandra
Fitzpatrick, Paul A.
Heydenreich, Matthias
Landberg, Goran
Derese, Solomon
Avery, Vicky
Rissanen, Kari
Erdelyi, Mate
Yenesew, Abiy
[J]. JOURNAL OF NATURAL PRODUCTS, 2015, 78 (12): : 2932 - 2939
[8] Isolation and structure elucidation of bioactive compounds from the roots of the Tunisian Ononis angustissima L.
Ghribi, Lotfi
Waffo-Teguo, Pierre
Cluzet, Stephanie
Marchal, Axel
Marques, Jessica
Merillon, Jean-Michel
Ben Jannet, Hichem
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 25 (18) : 3825 - 3830
[9] Novel Benzil and Isoflavone Derivatives from Millettia dielsiana
Gong, Ting
Wang, Dong-Xiao
Chen, Ruo-Yun
Liu, Ping
Yu, De-Quan
[J]. PLANTA MEDICA, 2009, 75 (03) : 236 - 242
[10] Two new isoflavone glycosides from the vine stem of Millettia dielsiana
Gong, Ting
Zhang, Ting
Wang, Dong-xiao
Chen, Ruo-yun
Liu, Ping
Yu, De-quan
[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 16 (02) : 181 - 186

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