Novel Non-invasive Strategy for Spinal Neuromodulation to Control Human Locomotion

被引：12
作者：
Moshonkina, Tatiana [1 ]
Grishin, Alexander [1 ]
Bogacheva, Irina [1 ]
Gorodnichev, Ruslan [2 ]
Ovechkin, Alexander [3 ,4 ]
Siu, Ricardo [3 ]
Edgerton, V. Reggie [5 ,6 ,7 ]
Gerasimenko, Yury [1 ,8 ]
机构：
[1] Russian Acad Sci, Pavlov Inst Physiol, St Petersburg, Russia
[2] Velikie Luki State Acad Phys Educ & Sports, Velikiye Luki, Russia
[3] Univ Louisville, Univ Louisville Hlth, Frazier Rehab Inst, Kentucky Spinal Cord Injury Res Ctr, Louisville, KY 40292 USA
[4] Univ Louisville, Dept Neurol Surg, Louisville, KY 40292 USA
[5] Univ Calif Los Angeles, Dept Neurobiol & Neurosurg, Los Angeles, CA USA
[6] Univ Autonoma Barcelona, Hosp Neurorehabil, Inst Guttmann, Inst Univ, Barcelona, Spain
[7] Univ Technol Sydney, Ctr Neurosci & Regenerat Med, Fac Sci, Ultimo, NSW, Australia
[8] Univ Louisville, Dept Physiol & Biophys, Louisville, KY 40292 USA
来源：
FRONTIERS IN HUMAN NEUROSCIENCE | 2021年 / 14卷
基金：
美国国家卫生研究院;
关键词：
neuromodulation; paralysis; transcutaneous electrical spinal cord stimulation; humans; motor pools; EPIDURAL STIMULATION; CORD; MODULATION; ACTIVATION; GENERATE; WALKING;
D O I：
10.3389/fnhum.2020.622533
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
[No abstract available]
引用
收藏
页数：4
相关论文
共 21 条
[1]   Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury [J].
Angeli, Claudia A. ;
Boakye, Maxwell ;
Morton, Rebekah A. ;
Vogt, Justin ;
Benton, Kristin ;
Chen, Yangshen ;
Ferreira, Christie K. ;
Harkema, Susan J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (13) :1244-1250
[2]   Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans [J].
Angeli, Claudia A. ;
Edgerton, V. Reggie ;
Gerasimenko, Yury P. ;
Harkema, Susan J. .
BRAIN, 2014, 137 :1394-1409
[3]   Contribution of Commissural Projections to Bulbospinal Activation of Locomotion in the In Vitro Neonatal Rat Spinal Cord [J].
Cowley, Kristine C. ;
Zaporozhets, Eugene ;
Joundi, Raed A. ;
Schmidt, Brian J. .
JOURNAL OF NEUROPHYSIOLOGY, 2009, 101 (03) :1171-1178
[4]   Neuroanatomical Basis for Cholinergic Modulation of Locomotor Networks by Sacral Relay Neurons With Ascending Lumbar Projections [J].
Finkel, Eran ;
Etlin, Alex ;
Cherniak, Meir ;
Mor, Yoav ;
Lev-Tov, Aharon ;
Anglister, Lili .
JOURNAL OF COMPARATIVE NEUROLOGY, 2014, 522 (15) :3437-3455
[5]   Alpha-1 adrenoceptor agonists generate a "fast" NMDA receptor-independent motor rhythm in the neonatal rat spinal cord [J].
Gabbay, H ;
Lev-Tov, A .
JOURNAL OF NEUROPHYSIOLOGY, 2004, 92 (02) :997-1010
[6]   Control of locomotor activity in humans and animals in the absence of supraspinal influences [J].
Gerasimenko Yu.P. ;
Makarovskii A.N. ;
Nikitin O.A. .
Neuroscience and Behavioral Physiology, 2002, 32 (4) :417-423
[7]   Epidural stimulation: Comparison of the spinal circuits that generate and control locomotion in rats, cats and humans [J].
Gerasimenko, Yury ;
Roy, Roland R. ;
Edgerton, V. Reggie .
EXPERIMENTAL NEUROLOGY, 2008, 209 (02) :417-425
[8]   Rostral lumbar segments are the key controllers of hindlimb locomotor rhythmicity in the adult spinal rat [J].
Gerasimenko, Yury ;
Preston, Chet ;
Zhong, Hui ;
Roy, Roland R. ;
Edgerton, V. Reggie ;
Shah, Prithvi K. .
JOURNAL OF NEUROPHYSIOLOGY, 2019, 122 (02) :585-600
[9]   Transcutaneous electrical spinal-cord stimulation in humans [J].
Gerasimenko, Yury ;
Gorodnichev, Ruslan ;
Moshonkina, Tatiana ;
Sayenko, Dimitry ;
Gad, Parag ;
Edgerton, V. Reggie .
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE, 2015, 58 (04) :225-231
[10]   Initiation and modulation of locomotor circuitry output with multisite transcutaneous electrical stimulation of the spinal cord in noninjured humans [J].
Gerasimenko, Yury ;
Gorodnichev, Ruslan ;
Puhov, Aleksandr ;
Moshonkina, Tatiana ;
Savochin, Aleksandr ;
Selionov, Victor ;
Roy, Roland R. ;
Lu, Daniel C. ;
Edgerton, V. Reggie .
JOURNAL OF NEUROPHYSIOLOGY, 2015, 113 (03) :834-842
123