BIOLOGICAL CHEMISTRY Dehydrated but unharmed

被引：32
作者：
Benesch, Justin L. P. [1 ]
Robinson, Carol V. [1 ]
机构：
[1] Univ Oxford, Dept Chem, Oxford OX1 3QY, England
来源：
NATURE | 2009年 / 462卷 / 7273期
关键词：
MASS-SPECTROMETRY; PROTEIN COMPLEXES; GAS-PHASE; ELECTROSPRAY;
D O I：
10.1038/462576a
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The weakest interactions of protein complexes are thought to be lost when such assemblies are removed from their natural, watery environments. Not so, reveals a study in the vacuum chamber of a mass spectrometer.
引用
收藏
页码：576 / 577
页数：2
相关论文
共 10 条
  • [1] Micelles protect membrane complexes from solution to vacuum
    Barrera, Nelson P.
    Di Bartolo, Natalie
    Booth, Paula J.
    Robinson, Carol V.
    [J]. SCIENCE, 2008, 321 (5886) : 243 - 246
  • [2] Protein complexes in the gas phase: Technology for structural genomics and proteomics
    Benesch, Justin L. P.
    Ruotolo, Brandon T.
    Simmons, Douglas A.
    Robinson, Carol V.
    [J]. CHEMICAL REVIEWS, 2007, 107 (08) : 3544 - 3567
  • [3] Stepwise evolution of protein native structure with electrospray into the gas phase, 10-12 to 102 S
    Breuker, Kathrin
    McLafferty, Fred W.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (47) : 18145 - 18152
  • [4] Femtosecond diffractive imaging with a soft-X-ray free-electron laser
    Chapman, Henry N.
    Barty, Anton
    Bogan, Michael J.
    Boutet, Sebastien
    Frank, Matthias
    Hau-Riege, Stefan P.
    Marchesini, Stefano
    Woods, Bruce W.
    Bajt, Sasa
    Benner, Henry
    London, Richard A.
    Ploenjes, Elke
    Kuhlmann, Marion
    Treusch, Rolf
    Duesterer, Stefan
    Tschentscher, Thomas
    Schneider, Jochen R.
    Spiller, Eberhard
    Moeller, Thomas
    Bostedt, Christoph
    Hoener, Matthias
    Shapiro, David A.
    Hodgson, Keith O.
    Van der Spoel, David
    Burmeister, Florian
    Bergh, Magnus
    Caleman, Carl
    Huldt, Goesta
    Seibert, M. Marvin
    Maia, Filipe R. N. C.
    Lee, Richard W.
    Szoeke, Abraham
    Timneanu, Nicusor
    Hajdu, Janos
    [J]. NATURE PHYSICS, 2006, 2 (12) : 839 - 843
  • [5] Improving enzymes by using them in organic solvents
    Klibanov, AM
    [J]. NATURE, 2001, 409 (6817) : 241 - 246
  • [6] Hydrophobic Protein-Ligand Interactions Preserved in the Gas Phase
    Liu, Lan
    Bagal, Dhanashri
    Kitova, Elena N.
    Schnier, Paul D.
    Klassen, John S.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (44) : 15980 - +
  • [7] Loo JA, 1997, MASS SPECTROM REV, V16, P1
  • [8] The molecular sociology of the cell
    Robinson, Carol V.
    Sali, Andrej
    Baumeister, Wolfgang
    [J]. NATURE, 2007, 450 (7172) : 973 - 982
  • [9] Chaperonin Complexes Monitored by Ion Mobility Mass Spectrometry
    van Duijn, Esther
    Barendregt, Arjan
    Synowsky, Silvia
    Versluis, Cees
    Heck, Albert J. R.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (04) : 1452 - 1459
  • [10] Intermolecular interactions in biomolecular systems examined by mass spectrometry
    Wyttenbach, Thomas
    Bowers, Michael T.
    [J]. ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 2007, 58 (511-533) : 511 - 533
1