Human Papillomavirus Antibody Reference Reagents for Use in Postvaccination Surveillance Serology

被引：16

作者：

Bissett, Sara L. ^{[1
]}

Wilkinson, Dianna ^{[2
]}

Tettmar, Kate I. ^{[3
]}

Jones, Nicky ^{[2
]}

Stanford, Elaine ^{[4
]}

Panicker, Gitika ^{[5
]}

Faust, Helena ^{[6
]}

Borrow, Ray ^{[4
]}

Soldan, Kate ^{[1
]}

Unger, Elizabeth R. ^{[5
]}

Dillner, Joakim ^{[6
]}

Minor, Philip ^{[2
]}

Beddows, Simon ^{[1
]}

机构：

[1] Hlth Protect Agcy, Ctr Infect, London, England

[2] Natl Inst Biol Stand & Controls, Potters Bar, Herts, England

[3] NHS Blood & Transplant, London, England

[4] Hlth Protect Agcy, Vaccine Evaluat & Seroepidemiol Unit, Manchester, Lancs, England

[5] Ctr Dis Control & Prevent, Global WHO HPV Reference Lab, Atlanta, GA USA

[6] Malmo Univ Hosp, Global WHO HPV Reference Lab, Malmo, Sweden

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2012年 / 19卷 / 03期

基金：

英国医学研究理事会;

关键词：

PARTICLE VACCINE; HPV; NEUTRALIZATION; VALIDATION; INFECTION; EFFICACY; WOMEN; ASSAY;

D O I：

10.1128/CVI.05641-11

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Suitably controlled serosurveillance surveys are essential for evaluating human papillomavirus (HPV) immunization programs. A panel of plasma samples from 18-year-old females was assembled, the majority of the samples being from recipients of the bivalent HPV vaccine. Antibody specificities were evaluated by three independent laboratories, and 3 pools that displayed no antibodies to any HPV type tested or intermediate or high levels of antibody to HPV16, HPV18, HPV31, and HPV45 were created. These pools will be useful as control reagents for HPV serology.

引用

页码：449 / 451

页数：3

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