Ketogenic diet in migraine: rationale, findings and perspectives

被引：55

作者：

Barbanti, Piero ^{[1
]}

Fofi, Luisa ^{[1
]}

Aurilia, Cinzia ^{[1
]}

Egeo, Gabriella ^{[1
]}

Caprio, Massimiliano ^{[2
,3
]}

机构：

[1] IRCCS San Raffaele Pisana, Dept Neurol Motor & Sensorial Sci, Headache & Pain Unit, Via Pisana 235, I-00163 Rome, Italy

[2] IRCCS San Raffaele Pisana, Lab Cardiovasc Endocrinol, Rome, Italy

[3] San Raffaele Roma Open Univ, Dept Human Sci & Promot Qual Life, Rome, Italy

来源：

NEUROLOGICAL SCIENCES | 2017年 / 38卷

关键词：

Migraine; Ketogenic diet; Treatment; Prevention; Disability; OXIDATIVE STRESS; DISEASE;

D O I：

10.1007/s10072-017-2889-6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ketogenic diet (KD) is an established treatment for refractory pediatric epilepsy and a promising therapy for diverse neurological diseases. Clinical data on KD in migraine-obtained from 150 patients investigated in case reports and prospective studies-suggest that KD may be a rapid onset effective prophylaxis for episodic and chronic migraine. KD would contribute to restore brain excitability and metabolism and to counteract neuroinflammation in migraine, although its precise mechanism is still unclear. Randomized controlled studies are needed to confirm the usefulness of KD in migraine and to investigate its optimal duration, repeatability, feasibility in normal weight subjects, efficacy in pediatric population and association to conventional migraine prophylaxis.

引用

收藏

页码：S111 / S115

页数：5

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