Water-soluble nanocrystals through dual-interaction ligands

被引:93
作者
Wu, Huimeng [1 ]
Zhu, Haizhen [2 ]
Zhuang, Jiaqi [1 ]
Yang, Shuo [1 ]
Liu, Chen [2 ]
Cao, Y. Charles [1 ]
机构
[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA
[2] Univ Florida, Dept Pathol, Gainesville, FL 32611 USA
关键词
fluorescent probes; hydrophobic interactions; ligand design; nanotechnology; water chemistry;
D O I
10.1002/anie.200800434
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) No fear of water: Hydrophobic nanocrystals (NCs) are converted into hydrophilic ones by dual-interaction ligands, which bind onto the surface of NCs by coordinate bonding and hydrophobic van der Waals interactions. The resulting NCs have high stability in aqueous solutions over a wide pH range (1-14), salt concentrations, and thermal treatments. Quantum dots coated with these ligands are excellent fluorescence labels for immunostaining tests. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:3730 / 3734
页数:5
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