G proteins and opioid receptor-mediated signalling

被引：137
作者：
Standifer, KM
Pasternak, GW
机构：
[1] MEM SLOAN KETTERING CANC CTR, GEORGE C COTZIAS LAB NEUROONCOL, NEW YORK, NY 10021 USA
[2] UNIV HOUSTON, DEPT PHARMACOL & PHARMACEUT SCI, HOUSTON, TX 77204 USA
来源：
CELLULAR SIGNALLING | 1997年 / 9卷 / 3-4期
关键词：
mu opioid receptor; delta opioid receptor; kappa(3) opioid receptor; kappa(1) opioid receptor; pertussis toxin; antisense oligodeoxynucleotides; analgesia; antinociception; cAMP accumulation; phospholipase C; adenylyl cyclase; ORL-1; KOR-3; orphanin FQ; nociception;
D O I：
10.1016/S0898-6568(96)00174-X
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Most opioid receptor-mediated functions appear to be mediated through G protein interactions, therefore an understanding of opioid signalling requires knowledge of those interactions. This review chronicles the studies examining these interactions for all the opioid receptor subtypes, both in vivo and in vitro. (C) 1997 Elsevier Science Inc.
引用
收藏
页码：237 / 248
页数：12
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