Homocysteinylation of metallothionein impairs intracellular redox Homeostasis - The enemy within!

被引:15
作者
Colgan, Stephen M. [1 ]
Austin, Richard C. [1 ]
机构
[1] Henderson Res Ctr, Hamilton, ON L8V 1C3, Canada
关键词
D O I
10.1161/01.ATV.0000254151.00086.26
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
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页码:8 / 11
页数:4
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共 51 条
[1]   Targeting of metallothionein by L-homocysteine - A novel mechanism for disruption of zinc and redox homeostasis [J].
Barbato, John C. ;
Catanescu, Otilia ;
Murray, Kelsey ;
DiBello, Patricia M. ;
Jacobsen, Donald W. .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (01) :49-54
[2]   ATHEROSCLEROSIS - BASIC MECHANISMS - OXIDATION, INFLAMMATION, AND GENETICS [J].
BERLINER, JA ;
NAVAB, M ;
FOGELMAN, AM ;
FRANK, JS ;
DEMER, LL ;
EDWARDS, PA ;
WATSON, AD ;
LUSIS, AJ .
CIRCULATION, 1995, 91 (09) :2488-2496
[3]   Egr-1 is a major vascular pathogenic transcription factor in atherosclerosis and restenosis [J].
Blaschke, F ;
Bruemmer, D ;
Law, RE .
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2004, 5 (03) :249-254
[4]   Homocysteine lowering and cardiovascular events after acute myocardial infarction [J].
Bonaa, KH ;
Njolstad, I ;
Ueland, PM ;
Schirmer, H ;
Tverdal, A ;
Steigen, T ;
Wang, H ;
Nordrehaug, JE ;
Arnesen, E ;
Rasmussen, K .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (15) :1578-1588
[5]   Effects of homocysteine on proliferation, necrosis, and apoptosis of vascular smooth muscle cells in culture and influence of folic acid [J].
Buemi, M ;
Marino, D ;
Di Pasquale, G ;
Floccari, F ;
Ruello, A ;
Aloisi, C ;
Corica, F ;
Senatore, M ;
Romeo, A ;
Frisina, N .
THROMBOSIS RESEARCH, 2001, 104 (03) :207-213
[6]   HYPERHOMOCYSTEINEMIA - AN INDEPENDENT RISK FACTOR FOR VASCULAR-DISEASE [J].
CLARKE, R ;
DALY, L ;
ROBINSON, K ;
NAUGHTEN, E ;
CAHALANE, S ;
FOWLER, B ;
GRAHAM, I .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (17) :1149-1155
[7]   Cerebral vascular dysfunction in methionine synthase-deficient mice [J].
Dayal, S ;
Devlin, AM ;
McCaw, RB ;
Liu, ML ;
Arning, E ;
Bottiglieri, T ;
Shane, B ;
Faraci, FM ;
Lentz, SR .
CIRCULATION, 2005, 112 (05) :737-744
[8]   Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice [J].
Dayal, S ;
Arning, E ;
Bottiglieri, T ;
Böger, RH ;
Sigmund, CD ;
Faraci, FM ;
Lentz, SR .
STROKE, 2004, 35 (08) :1957-1962
[9]   Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia [J].
Dayal, Sanjana ;
Wilson, Katina M. ;
Leo, Lorie ;
Arning, Erland ;
Bottiglieri, Teodoro ;
Lentz, Steven R. .
BLOOD, 2006, 108 (07) :2237-2243
[10]   Hyperhomocysteinemia and its role in the development of atherosclerosis [J].
de Koning, ABL ;
Werstuck, GH ;
Zhou, J ;
Austin, RC .
CLINICAL BIOCHEMISTRY, 2003, 36 (06) :431-441