Is instrument-free molecular detection possible?

被引:6
作者
Bau, Haim H. [1 ]
Liu, Changchun [1 ]
Mauk, Michael [1 ]
Song, Jinzhao [1 ]
机构
[1] Univ Penn, Dept Mech Engn & Appl Mech, Philadelphia, PA 19104 USA
关键词
Molecular; diagnostics; point-of-care; infectious diseases; mutant allele; nucleic acids; DNA; RNA; ENZYMATIC AMPLIFICATION; RIFAMPIN RESISTANCE; TUBERCULOSIS; DIAGNOSIS;
D O I
10.1080/14737159.2017.1374855
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
引用
收藏
页码:949 / 951
页数:3
相关论文
共 13 条
[1]  
Bau HH, 2016, United States Patent, Patent No. [9,476,102, 9476102]
[2]   Point-of-Care System for Detection of Mycobacterium tuberculosis and Rifampin Resistance in Sputum Samples [J].
Castan, Pablo ;
de Pablo, Alicia ;
Fernandez-Romero, Natalia ;
Miguel Rubio, Jose ;
Cobb, Benjamin D. ;
Mingorance, Jesus ;
Toro, Carlos .
JOURNAL OF CLINICAL MICROBIOLOGY, 2014, 52 (02) :502-507
[3]   Isothermal Amplification Using a Chemical Heating Device for Point-of-Care Detection of HIV-1 [J].
Curtis, Kelly A. ;
Rudolph, Donna L. ;
Nejad, Irene ;
Singleton, Jered ;
Beddoe, Andy ;
Weigl, Bernhard ;
LaBarre, Paul ;
Owen, S. Michele .
PLOS ONE, 2012, 7 (02)
[4]   A disposable, self-contained PCR chip [J].
Kim, Jitae ;
Byun, Doyoung ;
Mauk, Michael G. ;
Bau, Haim H. .
LAB ON A CHIP, 2009, 9 (04) :606-612
[5]   Smart cup: A minimally-instrumented, smartphone-based point-of-care molecular diagnostic device [J].
Liao, Shih-Chuan ;
Peng, Jing ;
Mauk, Michael G. ;
Awasthi, Sita ;
Song, Jinzhao ;
Friedman, Harvey ;
Bau, Haim H. ;
Liu, Changchun .
SENSORS AND ACTUATORS B-CHEMICAL, 2016, 229 :232-238
[6]   A high-efficiency superhydrophobic plasma separator [J].
Liu, Changchun ;
Liao, Shih-Chuan ;
Song, Jinzhao ;
Mauk, Michael G. ;
Li, Xuanwen ;
Wu, Gaoxiang ;
Ge, Dengteng ;
Greenberg, Robert M. ;
Yang, Shu ;
Bau, Haim H. .
LAB ON A CHIP, 2016, 16 (03) :553-560
[7]   Nuclemeter: A Reaction-Diffusion Based Method for Quantifying Nucleic Acids Undergoing Enzymatic Amplification [J].
Liu, Changchun ;
Sadik, Mohamed M. ;
Mauk, Michael G. ;
Edelstein, Paul H. ;
Bushman, Frederic D. ;
Gross, Robert ;
Bau, Haim H. .
SCIENTIFIC REPORTS, 2014, 4
[8]   A self-heating cartridge for molecular diagnostics [J].
Liu, Changchun ;
Mauk, Michael G. ;
Hart, Robert ;
Qiu, Xianbo ;
Bau, Haim H. .
LAB ON A CHIP, 2011, 11 (16) :2686-2692
[9]   An isothermal amplification reactor with an integrated isolation membrane for point-of-care detection of infectious diseases [J].
Liu, Changchun ;
Geva, Eran ;
Mauk, Michael ;
Qiu, Xianbo ;
Abrams, William R. ;
Malamud, Daniel ;
Curtis, Kelly ;
Owen, S. Michele ;
Bau, Haim H. .
ANALYST, 2011, 136 (10) :2069-2076
[10]   Amplification-Free Detection of Circulating microRNA Biomarkers from Body Fluids Based on Fluorogenic Oligonucleotide-Templated Reaction between Engineered Peptide Nucleic Acid Probes: Application to Prostate Cancer Diagnosis [J].
Metcalf, Gavin A. D. ;
Shibakawa, Akifumi ;
Patel, Hinesh ;
Sita-Lumsden, Ailsa ;
Zivi, Andrea ;
Rama, Nona ;
Bevan, Charlotte L. ;
Ladame, Sylvain .
ANALYTICAL CHEMISTRY, 2016, 88 (16) :8091-8098