Microbial production of diols as platform chemicals: Recent progresses

被引：215
作者：
Zeng, An-Ping [1 ]
Sabra, Wael [1 ,2 ]
机构：
[1] Hamburg Univ Technol, Inst Bioproc & Biosyst Engn, D-21071 Hamburg, Germany
[2] Univ Alexandria, Dept Microbiol, Fac Sci, Alexandria, Egypt
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2011年 / 22卷 / 06期
关键词：
ENHANCED 2,3-BUTANEDIOL PRODUCTION; KLEBSIELLA-PNEUMONIAE; 1,3-PROPANEDIOL PRODUCTION; GLYCEROL FERMENTATION; ENGINEERED STRAIN; PATHWAY ANALYSIS; CONVERSION; R(-)-1,2-PROPANEDIOL; MESO-2,3-BUTANEDIOL; STATE;
D O I：
10.1016/j.copbio.2011.05.005
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Diols are chemicals with two hydroxyl groups which have a wide range of appealing applications as chemicals and fuels. In particular, four diol compounds, namely 1,3-propanediol (1,3-PDO), 1,2-propanediol (1,2-PDO), 2,3-butanediol (2,3-BDO) and 1,4-butanediol (1,4-BDO) can be biotechnologioally produced by direct microbial bioconversion of renewable materials. These diols are considered as platform green chemicals. We review and discuss here the recent development in the microbial production of these diols, especially regarding the engineering of production strains and optimization of the fermentation processes.
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收藏
页码：749 / 757
页数：9
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