Detection and Molecular Characterization of Yellow Fever Virus, 2017, Brazil

被引：12

作者：

Figueiredo, P. O. ^{[1
]}

Silva, A. T. S. ^{[1
]}

Oliveira, J. S. ^{[1
]}

Marinho, P. E. ^{[1
]}

Rocha, F. T. ^{[2
]}

Domingos, G. P. ^{[2
]}

Poblete, P. C. P. ^{[3
]}

Oliveira, L. B. S. ^{[4
]}

Duarte, D. C. ^{[3
]}

Bonjardim, C. A. ^{[1
]}

Abrahao, J. S. ^{[1
]}

Kroon, E. G. ^{[1
]}

Drumond, B. P. ^{[1
]}

Oliveira, D. B. ^{[2
]}

Trindade, G. S. ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, Inst Ciencias Biol, Dept Microbiol, Lab Virus, Av Antonio Carlos 6627,Campus Pampulha, BR-31270901 Belo Horizonte, MG, Brazil

[2] Univ Fed Vales Jequitinhonha & Mucuri, Fac Med, Ctr Integrado Pesquisa Saude, Campus JK,Rodovia MGT 367,KM 583,5000, BR-39100000 Diamantina, MG, Brazil

[3] Zoovet Consultoria LTDA, Ave Amazonas 2474, BR-30180001 Belo Horizonte, MG, Brazil

[4] Pontificia Univ Catolica Minas Gerais, Rua Dom Jose Gaspar,702, BR-30535000 Belo Horizonte, MG, Brazil

来源：

ECOHEALTH | 2018年 / 15卷 / 04期

关键词：

Yellow fever virus; Non-human primates; Emerging infectious diseases; Zoonotic virus; Arboviruses; Outbreak; NONHUMAN-PRIMATES; OUTBREAK; STATE; RNA;

D O I：

10.1007/s10393-018-1364-z

中图分类号：

X176 [生物多样性保护];

学科分类号：

090705 ;

摘要：

At the end of 2016, Brazil experienced an unprecedented yellow fever (YF) outbreak. Clinical, molecular and ecological aspects of human and non-human primate (NHP) samples collected at the beginning of the outbreak are described in this study. Spatial distribution analyses demonstrated a strong overlap between human and NHP cases. Through molecular analyses, we showed that the outbreak had a sylvatic origin, caused by the South American genotype 1 YFV, which has already been shown to circulate in Brazil. As expected, the clusters of cases were identified in regions with a low vaccination coverage. Our findings highlight the importance of the synchronization of animal surveillance and health services to identify emerging YF cases, thereby promoting a better response to the vulnerable population.

引用

页码：864 / 870

页数：7

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