Synthesis of New Perfluoroalkylated 1,3,4-Oxadiazoles and 1,2,4-Triazoles Starting from 2-(Perfluoroalkyl)ethane Thiols

被引：3

作者：

Akremi, Ali ^{[1
]}

Beji, Mohamed ^{[1
]}

Baklouti, Ahmed ^{[1
]}

机构：

[1] Fac Sci Tunis, Dept Chem, Lab Struct Organ Chem, Tunis 2092, Tunisia

来源：

SYNTHETIC COMMUNICATIONS | 2011年 / 41卷 / 13期

关键词：

Aryloxysulfonylisocyanates; carbon disulfide; 1; 3; 4-oxadiazole; 2-(perfluoroalkyl)ethane thiols; 2; 4-triazole; DERIVATIVES; DESIGN;

D O I：

10.1080/00397911.2010.494816

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[image omitted] 5-{[2-(Perfluoroalkyl)ethylthio]methyl}-1,3,4-oxadiazole-2-thiones 4a, b and 4-amino-5-{[2-(perfluoroalkyl)ethylthio]methyl}-4H-1,2,4-triazole-3-thiones 5a, b have been prepared from 2-(perfluoroalkyl)ethane thiols 1a, b through a multistep reaction sequence. Compounds 4a, b were further reacted with aryloxysulfonylisocyanates to give the corresponding 5-{[2-(perfluoroalkyl)ethylthio]methyl}-N-(aryloxysulfonyl)-2-thioxo-1,3,4-oxadiazole-3(2H)-carboxamide 6a-d. The new products were obtained in good to moderate yields, and their structures were established on the basis of their infrared, NMR, and mass spectral data.

引用

页码：1990 / 1998

页数：9

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