The metallo-β-lactamases fall into two distinct phylogenetic groups

被引：45

作者：

Hall, BG ^{[1
]}

Salipante, SJ ^{[1
]}

Barlow, M ^{[1
]}

机构：

[1] Univ Rochester, Dept Biol, Rochester, NY 14627 USA

来源：

JOURNAL OF MOLECULAR EVOLUTION | 2003年 / 57卷 / 03期

关键词：

metallo-beta-lactamases; Ambler Class B; serine beta-lactamases;

D O I：

10.1007/s00239-003-2471-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Ambler Class B metallo-beta-lactamases fall into two distinct phylogenetic groups based on the observation that there is no significant sequence homology between the sequences of members of different groups. Structural alignments confirm that those groups are no more closely related to each other than are the three classes of serine beta-lactamases, Classes A, C, and D. We present phylogenies of these two groups and suggest a new classification scheme for the beta-lactamases.

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收藏

页码：249 / 254

页数：6

相关论文

共 19 条

[1] THE STRUCTURE OF BETA-LACTAMASES [J].

AMBLER, RP .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1980, 289 (1036) :321-331

[2] Plasmid location and molecular heterogeneity of the L1 and L2 β-lactamase genes of Stenotrophomonas maltophilia [J].

Avison, MB ;

Higgins, CS ;

von Heldreich, CJ ;

Bennett, PM ;

Walsh, TR .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (02) :413-419

[3] Phylogenetic analysis shows that the OXA β-lactamase genes have been on plasmids for millions of years [J].

Barlow, M ;

Hall, BG .

JOURNAL OF MOLECULAR EVOLUTION, 2002, 55 (03) :314-321

[4] Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing β-lactamases in Chryseobacterium meningosepticum [J].

Bellais, S ;

Aubert, D ;

Naas, T ;

Nordmann, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (07) :1878-1886

[5] The Legionella (Fluoribacter) gormanii metallo-β-lactamase:: a new member of the highly divergent lineage of molecular-subclass B3 β-lactamases [J].

Boschi, L ;

Mercuri, PS ;

Riccio, ML ;

Amicosante, G ;

Galleni, M ;

Frère, JM ;

Rossolini, GM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (06) :1538-1543

[6] A FUNCTIONAL CLASSIFICATION SCHEME FOR BETA-LACTAMASES AND ITS CORRELATION WITH MOLECULAR-STRUCTURE [J].

BUSH, K ;

JACOBY, GA ;

MEDEIROS, AA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (06) :1211-1233

[7] Standard numbering scheme for class B β-lactamases [J].

Galleni, M ;

Lamotte-Brasseur, J ;

Rossolini, GM ;

Spencer, J ;

Dideberg, O ;

Frère, JM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) :660-663

[8]

HALL BG, 2001, CODONALIGN

[9] MRBAYES: Bayesian inference of phylogenetic trees [J].

Huelsenbeck, JP ;

Ronquist, F .

BIOINFORMATICS, 2001, 17 (08) :754-755

[10] AMPC CEPHALOSPORINASE OF ESCHERICHIA-COLI K-12 HAS A DIFFERENT EVOLUTIONARY ORIGIN FROM THAT OF BETA-LACTAMASES OF THE PENICILLINASE TYPE [J].

JAURIN, B ;

GRUNDSTROM, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (08) :4897-4901