Prevalence and Mechanisms of Malnutrition in Patients With Advanced Liver Disease, and Nutrition Management Strategies

被引：248

作者：

Cheung, Kally ^{[1
]}

Lee, Samuel S. ^{[2
]}

Raman, Maitreyi ^{[3
]}

机构：

[1] Alberta Hlth Serv, Calgary, AB, Canada

[2] Univ Calgary, Dept Med, Liver Unit, Calgary, AB, Canada

[3] Univ Calgary, Dept Med, Div Gastroenterol, Calgary, AB, Canada

来源：

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | 2012年 / 10卷 / 02期

关键词：

Liver Disease; Nutrient Therapies; Diet; Cirrhosis; Malnutrition; MINIMAL HEPATIC-ENCEPHALOPATHY; SUBJECTIVE GLOBAL ASSESSMENT; ENERGY-EXPENDITURE; AMINO-ACID; FRUCTO-OLIGOSACCHARIDE; CIRRHOTIC-PATIENTS; GLUCOSE-TOLERANCE; BODY-COMPOSITION; DOUBLE-BLIND; FATTY-ACIDS;

D O I：

10.1016/j.cgh.2011.08.016

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Malnutrition is prevalent among cirrhotic patients and is an important prognostic factor. Etiologic factors include hypermetabolism, malabsorption, altered nutrient metabolism, and anorexia. It is a challenge to manage nutrition in cirrhotic patients because of alterations to metabolic and storage functions of the liver; use of traditional assessment tools, such as anthropometric and biometric measures, is difficult because of complications such as ascites and inflammation. In addition to meeting macro- and micronutrient requirements, the composition and timing of supplements have been proposed to affect efficacy of nutrition support. Studies have indicated that branched chain aromatic acid can be given as therapeutic nutrients, and that probiotics and nocturnal feeding improve patient outcomes.

引用

页码：117 / 125

页数：9

共 83 条

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