Catalytic Gold Nanoparticles for Nanoplasmonic Detection of DNA Hybridization

被引：396

作者：

Zheng, Xiaoxue ^{[1
]}

Liu, Qing ^{[1
,2
,3
]}

Jing, Chao ^{[2
,3
]}

Li, Yang ^{[1
,2
,3
]}

Li, Di ^{[1
]}

Luo, Weijie ^{[1
]}

Wen, Yanqin ^{[1
]}

He, Yao ^{[1
]}

Huang, Qing ^{[1
]}

Long, Yi-Tao ^{[2
,3
]}

Fan, Chunhai ^{[1
]}

机构：

[1] Chinese Acad Sci, Phys Biol Lab, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China

[2] E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

[3] E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 50期

基金：

中国国家自然科学基金;

关键词：

catalysis; DNA; gold nanoparticles; microscopy; nanoplasmonics; FREE COLORIMETRIC DETECTION; CHRONOCOULOMETRIC DNA; METAL NANOPARTICLES; MICRORNA EXPRESSION; MOLECULAR RULER; SINGLE GOLD; GROWTH; NANOSTRUCTURES; PLATFORM; PROBE;

D O I：

10.1002/anie.201105121

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

DNA hybridization can finely regulate the intrinsic glucose oxidase like catalytic activity of AuNPs owing to the marked difference in adsorption of single- and double-stranded DNA on its surface. A sensing strategy for DNA and microRNA is presented; in a different approach, this DNA-regulated AuNP catalysis was coupled with AuNP-mediated seed growth, which was monitored in real time and at a single-nanoparticle level. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：11994 / 11998

页数：5

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