Catalytic Gold Nanoparticles for Nanoplasmonic Detection of DNA Hybridization

被引：378
作者：
Zheng, Xiaoxue [1 ]
Liu, Qing [1 ,2 ,3 ]
Jing, Chao [2 ,3 ]
Li, Yang [1 ,2 ,3 ]
Li, Di [1 ]
Luo, Weijie [1 ]
Wen, Yanqin [1 ]
He, Yao [1 ]
Huang, Qing [1 ]
Long, Yi-Tao [2 ,3 ]
Fan, Chunhai [1 ]
机构：
[1] Chinese Acad Sci, Phys Biol Lab, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China
[2] E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China
[3] E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 50期
基金：
中国国家自然科学基金;
关键词：
catalysis; DNA; gold nanoparticles; microscopy; nanoplasmonics; FREE COLORIMETRIC DETECTION; CHRONOCOULOMETRIC DNA; METAL NANOPARTICLES; MICRORNA EXPRESSION; MOLECULAR RULER; SINGLE GOLD; GROWTH; NANOSTRUCTURES; PLATFORM; PROBE;
D O I：
10.1002/anie.201105121
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
DNA hybridization can finely regulate the intrinsic glucose oxidase like catalytic activity of AuNPs owing to the marked difference in adsorption of single- and double-stranded DNA on its surface. A sensing strategy for DNA and microRNA is presented; in a different approach, this DNA-regulated AuNP catalysis was coupled with AuNP-mediated seed growth, which was monitored in real time and at a single-nanoparticle level. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：11994 / 11998
页数：5
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