Impact of Total Ischemic Time on Clinical Outcomes in Patients With ST-Elevation Myocardial Infarction: Lost Time Is Never Found Again

被引:4
作者
Kurmi, Pradeep [1 ]
Tripathi, Vishwa D. [1 ]
Tripathi, Sunil K. [1 ]
机构
[1] Shyam Shah Med Coll, Dept Cardiol, Super Speciality Block, Rewa, India
关键词
total ischemia time; st-elevation myocardial infarction; mortality; door to balloon time; angiographic findings; TO-BALLOON TIME; SEGMENT ELEVATION; TASK-FORCE; MORTALITY; DOOR; REPERFUSION; SIZE; GUIDELINES; MANAGEMENT; DURATION;
D O I
10.7759/cureus.23143
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction A dedicated relationship between total ischemic time (TIT) and clinical outcomes has been reported in ST-elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention (PCI); however, this claim is yet to be clarified. Accordingly, this study was carried out to determine the association of TIT with in-hospital and one-year follow-up outcomes in STEMI patients undergoing primary PCI. Material and methodology Between December 2020 and December 2021, a total of 113 consecutive STEMI patients undergoing primary PCI were prospectively included. According to TIT, all patients were categorized into two groups: (a) shorter TIT (<180 minutes) and (b) prolonged TIT (>= 180 minutes). Data regarding baseline, clinical, and angiographic characteristics, as well as in-hospital and one-year follow-up outcomes were noted among the two groups. Results A total of 113 STEMI patients with a mean age of 69.3 +/- 13.6 years were studied, and males 192 (81.4%)] were predominately affected with STEMI. A median TIT was 348 minutes. Of 113, 30 (23.0%) patients had a TIT of <180 minutes and 83 (73.5%) had a TIT of >= 180 minutes. Prolonged ischemia duration was significantly associated with composite of death, rehospitalization, and revascularization (p=0.02) at one-year follow-up. Conclusion TIT can be considered a good quality indicator, together with door-to-balloon time and other clinical determinants, in order to improve survival in STEMI patients.
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